Can J Gastroenterol Hepatol. 2015 Mar;29(2):72-6. doi: 10.1155/2015/169190.
The cost of liver biopsy (LB) is publicly funded in British Columbia, while the cost of transient elastography (FibroScan [FS], Echosens, France) is not. Consequently, there is regional variation regarding FS access and monitoring of liver disease progression.
To evaluate patient preference for FS versus LB and to assess the willingness to self-pay for FS.
Questionnaires were distributed in clinic and via mail to LB-experienced and LB-naive patients who underwent FS at Vancouver General Hospital, Vancouver, British Columbia.
The overall response rate was 76%. Of the 422 respondents, 205 were LB-experienced. The mean age was 53.5 years, 50.2% were male, 54.7% were Caucasian, 38.2% had hepatitis C and 26.3% had an annual household income >$75,000. Overall, 95.4% of patients preferred FS to LB. FS was associated with greater comfort than LB, with the majority reporting no discomfort during FS (84.1% versus 7.8% for LB), no discomfort after (96.2% versus 14.6% LB) and no feelings of anxiety after FS explanation (78.2% versus 12.7% LB). FS was also associated with greater speed, with the majority reporting short test duration (97.2% versus 48.3% LB) and short wait for the test result (95.5% versus 30.2% LB). Most (75.3%) respondents were willing to self-pay for FS, with 26.3% willing to pay $25 to $49. Patients with unknown liver disease preferred LB (OR [FS preference] 0.20 [95% CI 0.07 to 0.53]).
FS was the preferred method of assessing liver fibrosis among patients, with the majority willing to self-pay. To ensure consistency in access, provincial funding for FS is needed. However, LB remains the procedure of choice for individuals with an unknown diagnosis.
在不列颠哥伦比亚省,肝活检(LB)的费用由公共资金支付,而瞬时弹性成像(FibroScan [FS],Echosens,法国)的费用则不由公共资金支付。因此,FS 的使用和监测肝脏疾病进展方面存在区域差异。
评估患者对 FS 与 LB 的偏好,并评估他们自付 FS 的意愿。
在温哥华总医院(温哥华,不列颠哥伦比亚省)进行 FS 的 LB 经验丰富和 LB 无经验的患者,通过门诊和邮寄的方式发放问卷。
总回复率为 76%。在 422 名受访者中,有 205 名有 LB 经验。平均年龄为 53.5 岁,50.2%为男性,54.7%为白种人,38.2%患有丙型肝炎,26.3%的家庭年收入超过 75,000 加元。总体而言,95.4%的患者更喜欢 FS 而不是 LB。FS 比 LB 更舒适,大多数患者报告 FS 期间无不适(84.1%比 LB 的 7.8%),FS 后无不适(96.2%比 LB 的 14.6%),FS 解释后无焦虑感(78.2%比 LB 的 12.7%)。FS 还与速度更快相关,大多数患者报告 FS 测试时间短(97.2%比 LB 的 48.3%),等待测试结果时间短(95.5%比 LB 的 30.2%)。大多数(75.3%)受访者愿意自付 FS 的费用,其中 26.3%愿意支付 25 至 49 加元。对于未知肝脏疾病的患者,他们更喜欢 LB(OR [FS 偏好] 0.20 [95%CI 0.07 至 0.53])。
在患者中,FS 是评估肝纤维化的首选方法,大多数患者愿意自付费用。为了确保 FS 的可及性一致,需要为 FS 提供省级资金。然而,对于没有明确诊断的患者,LB 仍然是首选的检查方法。