Li Bin, Zhang Miaomiao, Liu Wei, Wang Jianrong
a Department of Ophthalmology , The Second People's Hospital of Jinan , Jinan , P. R. China.
Curr Eye Res. 2016;41(2):215-21. doi: 10.3109/02713683.2015.1009635. Epub 2015 Sep 15.
To compare the efficacy and safety of two different traction suture (superior rectus traction suture and peripheral lamellar corneal traction suture) in patients undergoing trabeculectomy.
This retrospective trial compared outcomes of 385 eyes that underwent trabeculectomy with superior rectus traction suture (SRTS group; 206 eyes; 53.3%) and peripheral lamellar corneal traction suture (CTS group; 179 eyes; 46.7%). Qualified surgical success is defined as an intraocular pressure (IOP) between 6 and 21 mm Hg with or without topical anti-glaucoma medication.
After a follow-up of 24 months, the difference of IOP was significant (p = 0.042). The mean number of anti-glaucoma medications was 3.5 ± 0.6 and 3.5 ± 0.5 preoperatively (p = 1.000), whereas 0.18 ± 0.32 and 0.10 ± 0.39 at 24 months (p = 0.028). The 24-month qualified surgical success rates were 88.3% and 94.4% for both groups (p = 0.035; log-rank test). The difference between the two groups in regard to maximal bleb area is statistically significant (p = 0.011), with CTS group exhibiting more diffuse bleb area. The difference between the two groups in regard to the vascularity at the central and peripheral part of bleb is statistically significant (p = 0.019; p = 0.023, respectively). Encysted blebs was seen in 27 (13.1%) eyes in SRTS group and in 12 (6.7%) eyes in CTS group (p = 0.041).
The use of superior rectus traction suture is significantly associated with a lower success rate than corneal traction suture, suggesting that surgeons should use a corneal fixation suture if at all possible.
比较两种不同的牵引缝线(上直肌牵引缝线和周边板层角膜牵引缝线)在小梁切除术患者中的疗效和安全性。
这项回顾性试验比较了385只接受小梁切除术的眼睛的结果,其中206只眼睛采用上直肌牵引缝线(SRTS组;53.3%),179只眼睛采用周边板层角膜牵引缝线(CTS组;46.7%)。合格的手术成功定义为眼压(IOP)在6至21毫米汞柱之间,无论是否使用局部抗青光眼药物。
随访24个月后,眼压差异有统计学意义(p = 0.042)。术前抗青光眼药物的平均数量分别为3.5±0.6和3.5±0.5(p = 1.000),而在24个月时分别为0.18±0.32和0.10±0.39(p = 0.028)。两组24个月的合格手术成功率分别为88.3%和94.4%(p = 0.035;对数秩检验)。两组在最大滤泡面积方面的差异有统计学意义(p = 0.011),CTS组的滤泡面积更弥散。两组在滤泡中央和周边部分的血管化方面的差异有统计学意义(分别为p = 0.019;p = 0.023)。SRTS组有27只(13.1%)眼睛出现包裹性滤泡,CTS组有12只(6.7%)眼睛出现包裹性滤泡(p = 0.041)。
使用上直肌牵引缝线的成功率明显低于角膜牵引缝线,这表明外科医生应尽可能使用角膜固定缝线。