Edmund L, Mohammed W
Department of Pathology, San Fernando General Hospital, Trinidad and Tobago.
Faculty of Medical Sciences, The University of the West Indies, St Augustine, Trinidad and Tobago.
West Indian Med J. 2014 Jul 3;63(6):664-6. doi: 10.7727/wimj.2014.079.
Malakoplakia is an unusual chronic inflammatory response first described in the genitourinary tract by Michaelis and Gutmann in 1902. It is now known to occur in other locations including the gastrointestinal tract, skin, lungs and the central nervous system. Malakoplakia has been frequently misdiagnosed clinically as a malignant lesion. Similarly, when it occurs in the gastrointestinal tract (eg colon) in association with adenocarcinoma, it may lead to clinical and radiological overstaging of the tumour.
软斑病是一种罕见的慢性炎症反应,1902年由米夏埃利斯和古特曼首次在泌尿生殖道中描述。现在已知它会发生在其他部位,包括胃肠道、皮肤、肺部和中枢神经系统。软斑病在临床上经常被误诊为恶性病变。同样,当它与腺癌相关发生在胃肠道(如结肠)时,可能会导致肿瘤在临床和影像学上的分期过高。