Lee JongGyu, Lee Jong Un, Kim Kwang-Ryeol, Kim Dae-Hyun
Department of Neurosurgery, Daegu Catholic University School of Medicine, Daegu, Korea.
J Korean Neurosurg Soc. 2024 Aug 28. doi: 10.3340/jkns.2024.0077.
Malakoplakia is a rare chronic inflammatory disease that has been rarely reported in the genitourinary tract, gastrointestinal tract, adrenal glands, skin, lungs, bone, and endometrium. Central nervous system malakoplakia is extremely rare, and even then, it has only been reported in the cerebrum and cerebellum. A definite diagnosis of malakoplakia depends on microscopic detection of Michaelis-Gutmann bodies. We would like to present the case of a 61-year-old male who, after undergoing a liver transplant and receiving prolonged antibiotic treatment for Escherichia coli bacteremia, presented with quadriparesis and gait disturbance. The clinical and radiologic appearance of malakoplakia mimics that of malignant tumor. This is a condition with no established appropriate treatment and presents challenges due to its spinal cord location. However, this case presents a case of spinal cord malakoplakia and may provide newly differential diagnosis of an intramedullary mass in the spinal cord.
软斑病是一种罕见的慢性炎症性疾病，在泌尿生殖道、胃肠道、肾上腺、皮肤、肺、骨和子宫内膜中鲜有报道。中枢神经系统软斑病极为罕见，即便如此，也仅在大脑和小脑中有所报道。软斑病的明确诊断依赖于对迈克尔is - 古特曼小体的显微镜检测。我们在此报告一例61岁男性病例，该患者在接受肝移植并因大肠杆菌菌血症接受长期抗生素治疗后，出现四肢瘫痪和步态障碍。软斑病的临床和影像学表现类似于恶性肿瘤。这是一种尚无既定合适治疗方法的疾病，因其位于脊髓部位而带来挑战。然而，本病例呈现了一例脊髓软斑病，可能为脊髓内髓质肿块提供新的鉴别诊断。
