精神分裂症与致幻剂持续性感知障碍：一项临床研究。
Schizophrenia and hallucinogen persisting perception disorder: A clinical investigation.
作者信息
Lev-Ran Shaul, Feingold Daniel, Rudinski Dmitri, Katz Stefan, Arturo Lerner G
机构信息
Addiction Medicine Services, Department of Psychiatry, Sheba Medical Center, Tel Hashomer, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
出版信息
Am J Addict. 2015 Apr;24(3):197-199. doi: 10.1111/ajad.12204. Epub 2015 Mar 24.
BACKGROUND AND OBJECTIVES
We compared characteristics of schizophrenia patients with prior LSD use who developed hallucinogen persisting perception disorder (SCH+HPPD) with those who did not (SCH-HPPD).
METHODS
Data were collected for 37 subjects in the SCH+HPPD group and 43 subjects in the SCH-HPPD group.
RESULTS
Socio-demographics and positive symptom scores were similar between groups. Individuals in the SCHIZO+HPPD group scored lower on general psychopathology and negative symptoms scores.
DISCUSSION AND CONCLUSIONS
Individuals with schizophrenia and HPPD present with less severe psychopathology, despite persistent perceptual disturbances.
SCIENTIFIC SIGNIFICANCE
Our findings highlight the importance of further research into this subset of patients.
背景与目的
我们比较了曾使用麦角酸二乙酰胺（LSD）且出现致幻剂持续性感知障碍（SCH + HPPD）的精神分裂症患者与未出现该障碍（SCH - HPPD）的精神分裂症患者的特征。
方法
收集了37名SCH + HPPD组受试者和43名SCH - HPPD组受试者的数据。
结果
两组之间的社会人口统计学特征和阳性症状评分相似。SCHIZO + HPPD组个体在一般精神病理学和阴性症状评分上较低。
讨论与结论
患有精神分裂症和HPPD的个体尽管存在持续性感知障碍，但精神病理学症状较轻。
科学意义
我们的研究结果凸显了对这一患者亚组进行进一步研究的重要性。
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