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比较使用麦角酸二乙酰胺(LSD)后患有致幻剂持续性感知障碍(HPPD)的个体中,正向与负向体验者的触发因素与视觉障碍情况。

Comparing triggers to visual disturbances among individuals with positive vs negative experiences of hallucinogen-persisting perception disorder (HPPD) following LSD use.

作者信息

Lev-Ran Shaul, Feingold Daniel, Goodman Craig, Lerner Arturo G

机构信息

Lev Hasharon Mental Health Center, Pardessya, Israel.

Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Am J Addict. 2017 Sep;26(6):568-571. doi: 10.1111/ajad.12577. Epub 2017 Jun 27.

DOI:10.1111/ajad.12577
PMID:28654720
Abstract

BACKGROUND AND OJECTIVE

Exploring differences in visual disturbances and triggers between Hallucinogen-Persisting-Perceptual-Disorder (HPPD) Type I ("positive/benign") and II ("negative/distressing").

METHODS

Forty individuals with HPPD and prior LSD use completed clinical questionnaires.

RESULTS

The most common type of visual disturbances among individuals with HPPD I and II was slow movement of still objects and trailing phenomena, respectively. Those with HPPD I were more likely to report experiencing disturbances in dark environment, while looking at a still or moving object and during sexual intercourse.

DISCUSSION AND CONCLUSIONS

HPPD I and II differ in terms of visual disturbances and triggers, possibly representing different phenomena existing on the same spectrum.

SCIENTIFIC SIGNIFICANCE

Our study indicating differences in triggers to HPPD I and II adds to existing literature on differences in visual disturbances between the two subtypes. Further research elucidating additional differences between the subtypes of HPPD is needed. (Am J Addict 2017;26:568-571).

摘要

背景与目的

探究致幻剂持续性感知障碍(HPPD)I型(“阳性/良性”)和II型(“阴性/困扰性”)在视觉障碍及触发因素方面的差异。

方法

40名有过使用麦角酸二乙酰胺(LSD)经历且患有HPPD的个体完成了临床问卷。

结果

HPPD I型和II型个体中最常见的视觉障碍类型分别是静止物体的缓慢移动和拖尾现象。HPPD I型个体更有可能报告在黑暗环境中、注视静止或移动物体时以及性交过程中出现障碍。

讨论与结论

HPPD I型和II型在视觉障碍及触发因素方面存在差异,可能代表了同一谱系上存在的不同现象。

科学意义

我们的研究表明HPPD I型和II型在触发因素上存在差异,这为关于这两种亚型在视觉障碍方面差异的现有文献增添了内容。需要进一步研究以阐明HPPD各亚型之间的其他差异。(《美国成瘾杂志》2017年;26:568 - 571)

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