Matthieu Lilamand, MD MSc. Gérontopôle - Institut du Vieillissement, 37 Allées Jules Guesde. 31000 Toulouse France. Phone: +33 (0)5 61145657. Fax: +33 (0)5 61145640 email:
J Nutr Health Aging. 2015 Apr;19(4):383-8. doi: 10.1007/s12603-014-0533-1.
To examine whether the Mini Nutritional Assessment-Short Form (MNA-SF) score and its individual items are predictors of mortality in a nursing home population.
Prospective, secondary analysis from the Incidence of pNeumonia and related ConseqUences in nursing home Residents (INCUR) study with 1-year follow-up.
A total of 773 older persons (women 74.4%) living in 13 French nursing homes.
At baseline, nutritional status was assessed with the MNA-SF. Overall mortality rate was measured over a 12-month follow-up period after the baseline assessment visit. Cox proportional hazard models were performed to test the predictive capacity of the MNA-SF score and its single components for mortality.
Mean age of participants was 86.2 (standard deviation, SD 7.5) years. Mean MNA-SF score was 9.8 (SD 2.4). Among participants, 198 (25.6%) presented a normal nutritional status (12-14 points), 454 (58.7%) were at risk of malnutrition (8-11 points), and 121 (15.7%) were malnourished. After one year of follow-up, 135 (17.5%) participants had died. Age, female gender, baseline weight, BMI and MNA-SF were significant predictors of mortality whereas no specific chronic disease was. The total MNA-SF score was a significant predictor of mortality (Hazard Ratio=0.83; 95% CI 0.75-0.91; p<0.001), even after adjustment for potential confounders. Four individual items: weight loss, decrease in food intake, recent stress and BMI were independent predictors of mortality.
The MNA-SF appears to be an accurate predictor of one-year mortality in nursing home residents. Thus, this tool may be regarded not only as a nutritional screening tool, but also as an instrument for identifying the most-at-risk individuals in this population.
探讨简易营养评估量表(MNA-SF)评分及其各单项指标是否可预测养老院人群的死亡率。
对 Incur 研究(法国 13 家养老院居民肺炎发病率及相关后果的研究)的二次分析,前瞻性研究,随访 1 年。
共纳入 773 名老年人(女性占 74.4%),居住在法国 13 家养老院。
于基线时采用 MNA-SF 评估营养状况。在基线评估后 12 个月的随访期间,测量总死亡率。采用 Cox 比例风险模型检验 MNA-SF 评分及其各单项指标对死亡率的预测能力。
参与者的平均年龄为 86.2 岁(标准差为 7.5 岁),平均 MNA-SF 评分为 9.8 分(标准差为 2.4 分)。参与者中,198 名(25.6%)营养状况正常(12-14 分),454 名(58.7%)存在营养不良风险(8-11 分),121 名(15.7%)存在营养不良。随访 1 年后,135 名(17.5%)参与者死亡。年龄、女性、基线体重、BMI 和 MNA-SF 是死亡率的显著预测因素,而特定的慢性疾病不是。MNA-SF 总分是死亡率的显著预测因素(风险比=0.83;95%置信区间为 0.75-0.91;p<0.001),即使在调整了潜在混杂因素后也是如此。体重减轻、食物摄入量减少、近期压力和 BMI 这 4 个单项指标是死亡率的独立预测因素。
MNA-SF 似乎是养老院居民 1 年死亡率的准确预测指标。因此,该工具不仅可以作为营养筛查工具,还可以作为识别该人群中高危个体的工具。