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由不规则毛霉引起的原发性皮肤毛霉病。

Primary cutaneous mucormycosis caused by Mucor irregularis.

作者信息

Xia X J, Shen H, Liu Z H

机构信息

Department of Dermatology, Third Hospital of Hangzhou, Hangzhou, China.

出版信息

Clin Exp Dermatol. 2015 Dec;40(8):875-8. doi: 10.1111/ced.12642. Epub 2015 Mar 25.

DOI:10.1111/ced.12642
PMID:25810249
Abstract

We describe a case of primary cutaneous mucormycosis in a 44-year-old man with an 18-month history of infiltrative erythematous plaques and haemorrhagic crusting on the dorsum of his left hand. The isolate was identified as Mucor irregularis (formerly Rhizomucor variabilis) based on the fungus morphology and DNA sequencing results. Improvement was observed after a 6-month treatment course of itraconazole. No recrudescence was seen during a follow-up of 23 months after treatment.

摘要

我们描述了一例44岁男性原发性皮肤毛霉病病例,该患者左手背部有18个月的浸润性红斑斑块和出血性结痂病史。根据真菌形态学和DNA测序结果,分离株被鉴定为不规则毛霉(以前称为多变根毛霉)。在接受6个月的伊曲康唑治疗后观察到病情改善。治疗后23个月的随访期间未见复发。

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引用本文的文献

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Global Cutaneous Mucormycosis: A Systematic Review.全球皮肤毛霉病:一项系统评价
J Fungi (Basel). 2022 Feb 16;8(2):194. doi: 10.3390/jof8020194.
2
Successful treatment of a patient with cutaneous co-infection caused by Mucor irregularis and Klebsiella pneumoniae.成功治疗一例由不规则毛霉和肺炎克雷伯菌引起的皮肤合并感染患者。
An Bras Dermatol. 2020 Sep-Oct;95(5):623-626. doi: 10.1016/j.abd.2020.03.004. Epub 2020 Jun 16.
3
Disfiguring Mucor irregularis Infection Cured by Amphotericin B and Itraconazole: A Case Report and Treatment Experience.
两性霉素 B 和伊曲康唑治愈致残性不规则毛霉感染:病例报告及治疗经验。
Mycopathologia. 2019 Oct;184(5):677-682. doi: 10.1007/s11046-019-00380-5. Epub 2019 Sep 17.
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Cutaneous mucormycosis.皮肤毛霉病
An Bras Dermatol. 2017 May-Jun;92(3):304-311. doi: 10.1590/abd1806-4841.20176614.
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The influence of the mating type on virulence of Mucor irregularis.交配型对不规则毛霉毒力的影响。
Sci Rep. 2017 Sep 6;7(1):10629. doi: 10.1038/s41598-017-10954-2.
6
Changing Epidemiology of Mucoralean Fungi: Chronic Cutaneous Infection Caused by Mucor irregularis.毛霉目真菌流行病学的变化:不规则毛霉引起的慢性皮肤感染
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