Shekar Vandana, Sikander Jeelani, Rangdhol Vishwanath, Naidu Madhulika
Department of Oral Medicine and Radiology, Indira Gandhi Institute of Dental Sciences, Puducherry, India.
J Nat Sci Biol Med. 2015 Jan-Jun;6(1):226-8. doi: 10.4103/0976-9668.149195.
Mucormycosis is a rare opportunistic aggressive and fatal infection caused by mucor fungus. Seven types of mucormycosis are identified based on the extension and involvement of the lesion, of which the rhino orbital mucormycosis is most common in the head and neck region. Although it is widely spread in nature, clinical cases are rare and observed only in immunocompromised patients and patients with uncontrolled diabetes mellitus. Early symptoms include fever, nasal ulceration or necrosis, periorbital edema or facial swelling, paresthesia and reduced vision. Involvement of cranial nerves although not common, facial nerve palsy is a rare finding. The infection may spread through cribriform plate to the brain resulting in extensive cerebellar infarctions. Timely diagnosis and early recognition of the signs and symptoms, correction of underlying medical disorders, and aggressive medical and surgical intervention are necessary for successful therapeutic outcome.
毛霉菌病是一种由毛霉菌引起的罕见的、侵袭性且致命的机会性感染。根据病变的扩展和累及情况，可识别出七种类型的毛霉菌病，其中鼻眶毛霉菌病在头颈部区域最为常见。尽管它在自然界广泛传播，但临床病例罕见，仅在免疫功能低下的患者和糖尿病控制不佳的患者中观察到。早期症状包括发热、鼻溃疡或坏死、眶周水肿或面部肿胀、感觉异常和视力下降。虽然颅神经受累并不常见，但面神经麻痹是一种罕见的表现。感染可能通过筛板扩散至脑部，导致广泛的小脑梗死。为获得成功的治疗结果，及时诊断并早期识别体征和症状、纠正潜在的内科疾病以及积极的药物和手术干预是必要的。
