Pecket P, Schattner A
J Neurol Neurosurg Psychiatry. 1982 Jul;45(7):652-5. doi: 10.1136/jnnp.45.7.652.
In a series of 126 patients with Bell's palsy, chemical or overt diabetes mellitus was found in 39% of the cases. A high frequency of disturbances of taste was found in the patients who had no diabetes (83%), as compared to only 14% of diabetic patients whose taste was affected (p less than 0 .001). Thus, the usual site of facial nerve lesion in diabetics appears to be distal to the chorda tympani, while in patients whose glucose tolerance is normal, no such selectivity exists. This may only be explained by a diabetes-related pathogenesis and a vascular rather than a generalised "metabolic" impairment is postulated, leading to a localised facial nerve ischaemia in the distal part of the Fallopian canal. Thus, some cases of Bell's palsy may in fact be a diabetic mononeuropathy.
在一系列126例贝尔面瘫患者中,39%的病例发现有化学性或显性糖尿病。未患糖尿病的患者味觉障碍发生率较高(83%),而味觉受影响的糖尿病患者仅为14%(p<0.001)。因此,糖尿病患者面神经病变的常见部位似乎在鼓索神经远端,而糖耐量正常的患者不存在这种选择性。这只能用与糖尿病相关的发病机制来解释,推测是血管性而非全身性“代谢”损伤,导致面神经管远端局部缺血。因此,一些贝尔面瘫病例实际上可能是糖尿病性单神经病。