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新型冠状病毒肺炎相关毛霉菌病并发症之面神经麻痹:病例系列报道

Facial Nerve Palsy as Complication in COVID-19 Associated Mucormycosis: A Case Series.

作者信息

Reddy Prashanthi, Parihar Ajay, Singh Renu, Ac Varsha, Sutare Ajay

机构信息

Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, IND.

出版信息

Cureus. 2022 Dec 29;14(12):e33077. doi: 10.7759/cureus.33077. eCollection 2022 Dec.

DOI:10.7759/cureus.33077
PMID:36726898
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9886373/
Abstract

Mucormycosis is an opportunistic fungal infection indicating a high mortality rate. Among six varieties of involved sites, rhino cerebral mucormycosis (RCM) is not the most uncommon. During the COVID-19 pandemic, with the increase, in predisposing conditions incidence rate of mucormycosis progressed. For aggressive treatment, an early diagnosis can be armored to reduce morbidity and mortality. Clinically RCM poses non-specific symptoms and signs delaying diagnosis. This is associated with orbital cellulitis and sinusitis, one-sided headache behind the eye, diplopia, blurring of visions, nasal congestion, rhinorrhea, epistaxis, nasal hypoesthesia, facial pain and numbness, and a history of black nasal discharge. Not commonly the complications of cranial nerve involvement have been reported. In the present case series, three presentations of facial nerve palsy in COVID-19 associated with mucormycosis are added to the literature database.

摘要

毛霉菌病是一种机会性真菌感染,死亡率很高。在六个受累部位的类型中,鼻脑型毛霉菌病(RCM)并非最不常见。在新冠疫情期间,随着易感条件的增加,毛霉菌病的发病率有所上升。为了进行积极治疗,可以通过早期诊断来降低发病率和死亡率。临床上,RCM表现出非特异性症状和体征,从而延迟诊断。这与眼眶蜂窝织炎和鼻窦炎、眼后单侧头痛、复视、视力模糊、鼻塞、流涕、鼻出血、鼻感觉减退、面部疼痛和麻木以及黑色鼻分泌物病史有关。关于颅神经受累并发症的报道并不常见。在本病例系列中,新冠疫情相关毛霉菌病伴发面神经麻痹的三种表现被纳入文献数据库。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/96c4d6439f86/cureus-0014-00000033077-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/d616497bf6e9/cureus-0014-00000033077-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/578ab4eee6b3/cureus-0014-00000033077-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/442c41a39801/cureus-0014-00000033077-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/27b81ff5a8b8/cureus-0014-00000033077-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/a8f33cfdc7fd/cureus-0014-00000033077-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/495008de89df/cureus-0014-00000033077-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/1b2fb45838ef/cureus-0014-00000033077-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/0224d86c3348/cureus-0014-00000033077-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/96c4d6439f86/cureus-0014-00000033077-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/d616497bf6e9/cureus-0014-00000033077-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/578ab4eee6b3/cureus-0014-00000033077-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/442c41a39801/cureus-0014-00000033077-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/27b81ff5a8b8/cureus-0014-00000033077-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/a8f33cfdc7fd/cureus-0014-00000033077-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/495008de89df/cureus-0014-00000033077-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/1b2fb45838ef/cureus-0014-00000033077-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/0224d86c3348/cureus-0014-00000033077-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15b/9886373/96c4d6439f86/cureus-0014-00000033077-i09.jpg

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本文引用的文献

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Mucormycosis in COVID-19: A systematic review of cases reported worldwide and in India.COVID-19 相关毛霉菌病:全球及印度病例报告的系统综述。
Diabetes Metab Syndr. 2021 Jul-Aug;15(4):102146. doi: 10.1016/j.dsx.2021.05.019. Epub 2021 May 21.
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Bell's Palsy as a Late Neurologic Manifestation of COVID-19 Infection.
贝尔麻痹作为新型冠状病毒感染的迟发性神经表现
Cureus. 2021 Mar 14;13(3):e13881. doi: 10.7759/cureus.13881.
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Facial Nerve Palsy: An Unusual Presentation in Patients with Rhino Cerebral Mucormycosis.面神经麻痹:鼻脑型毛霉菌病患者的一种不寻常表现。
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