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宫颈异位妊娠

Cervical ectopic pregnancy.

作者信息

Samal Sunil Kumar, Rathod Setu

机构信息

Department of Obstetrics and Gynaecology, Mahatma Gandhi Medical College & Research Institute, Puducherry, India.

出版信息

J Nat Sci Biol Med. 2015 Jan-Jun;6(1):257-60. doi: 10.4103/0976-9668.149221.

Abstract

Cervical pregnancy is a rare type of ectopic pregnancy and it represents <1% of all ectopic pregnancies. Early diagnosis and medical management with systemic or local administration of methotrexate is the treatment of choice. If the pregnancy is disturbed, it may lead to massive hemorrhage, which may require hysterectomy to save the patient. We report three cases of cervical pregnancy managed successfully with different approaches of management. Our first case, 28 years old G3P2L2 with previous two lower segment cesarean sections, presented with bleeding per vaginum following 6 weeks of amenorrhea. Clinical examination followed by transvaginal ultrasound confirmed the diagnosis of cervical pregnancy. Total abdominal hysterectomy was done in view of intractable bleeding to save the patient. The second case, a 26-year-old second gravida with previous normal vaginal delivery presented with pain abdomen and single episode of spotting per vaginum following 7 weeks of amenorrhea. Transvaginal ultrasound revealed empty endometrial cavity, closed internal os with gestational sac containing live fetus of 7 weeks gestational age in cervical canal and she was treated with intra-amniotic potassium chloride followed by systemic methotrexate. Follow up with serum beta human chorionic gonadotropin level revealed successful outcome. Our third case, a 27-year-old primigravida with history of infertility treatment admitted with complaints of bleeding per vaginum for 1 day following 8 weeks amenorrhea. She was diagnosed as cervical pregnancy by clinical examination, confirmed by transvaginal ultrasonography and subsequently managed by dilation and curettage with intracervical Foleys' ballon tamponade.

摘要

宫颈妊娠是一种罕见的异位妊娠类型,占所有异位妊娠的比例不到1%。早期诊断并采用全身或局部应用甲氨蝶呤进行药物治疗是首选的治疗方法。如果妊娠受到干扰,可能会导致大量出血,这可能需要进行子宫切除术以挽救患者生命。我们报告了三例采用不同管理方法成功治疗的宫颈妊娠病例。我们的首例病例为一名28岁、孕3产2、有两次下段剖宫产史的女性,停经6周后出现阴道出血。临床检查及经阴道超声检查确诊为宫颈妊娠。鉴于出血难以控制,为挽救患者生命,实施了全腹子宫切除术。第二例病例为一名26岁、孕2产0、既往顺产的女性,停经7周后出现腹痛及单次阴道少量出血。经阴道超声显示子宫内膜腔空虚,宫颈内口关闭,宫颈管内有一个妊娠囊,囊内有一个7周龄的活胎,随后对其进行了羊膜腔内注射氯化钾,之后全身应用甲氨蝶呤治疗。随访血清β-人绒毛膜促性腺激素水平显示治疗成功。我们的第三例病例为一名27岁、初孕、有不孕症治疗史的女性,停经8周后因阴道出血1天入院。经临床检查诊断为宫颈妊娠,经阴道超声检查确诊,随后通过扩张刮宫术并在宫颈内放置福莱氏球囊填塞进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3003/4367055/c1eda6c43001/JNSBM-6-257-g001.jpg

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