Yıldırım Fatma, Kara İskender, Yıldız Sedat, Akyürek Nalan, Acar Kadir, Türkoglu Melda, Aygencel Gülbin
Department of Pulmonary Medicine, Gazi University Faculty of Medicine, Ankara, Turkey.
Department of Anesthesiology and Reanimation, Gazi University Faculty of Medicine, Ankara, Turkey.
Case Rep Pulmonol. 2015;2015:945268. doi: 10.1155/2015/945268. Epub 2015 Feb 24.
Richter's transformation (RT) refers to the development of aggressive lymphoma during the course of CLL. Clinically, patients with RT present with an aggressive disease course with rapidly enlarging lymph nodes, hepatosplenomegaly, and elevated serum lactate dehydrogenase levels. But rarely it presents with extra nodal organ involvement at the beginning. Common sites of extra nodal involvement are the gastrointestinal tract, eye, central nervous system, lung, and kidney. We are reporting this case that was presented with RT in the lung involvement diagnosed while researching cavitary lesion etiology.
里氏转化(RT)是指在慢性淋巴细胞白血病(CLL)病程中侵袭性淋巴瘤的发生。临床上,RT患者表现为侵袭性病程,伴有淋巴结迅速肿大、肝脾肿大和血清乳酸脱氢酶水平升高。但很少有患者一开始就出现结外器官受累。结外受累的常见部位是胃肠道、眼睛、中枢神经系统、肺和肾脏。我们报告了这例在研究空洞性病变病因时诊断为肺部受累的RT病例。