Bhandary Sujatha P, Papadimos Thomas J, Essandoh Michael K, Apostolakis John
Department of Anesthesiology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Department of Cardiothoracic Anesthesiology, Cleveland Clinic Main Campus, Cleveland, Ohio, USA.
Int J Crit Illn Inj Sci. 2015 Jan-Mar;5(1):56-8. doi: 10.4103/2229-5151.152347.
Thrombosis is a potential life-threatening complication in patients undergoing cardiac surgery. Various clinical and heritable conditions, like cancer, trauma, immobilization, the presence of factor V Leiden or prothrombin 20210A, deficiency of or resistance to the inhibitor proteins C, S, or antithrombin, elevated levels of coagulation proteins, antiphospholipid antibody syndrome, pregnancy, and the use of exogenous hormones, may contribute to catastrophic thrombosis. Massive thrombi with cerebrovascular and cardiovascular events develop in patients with polycythemia vera (PV). However, thrombus formation in the cardiac chambers is extremely rare. We report a case of massive intracardiac thrombosis in a patient undergoing coronary artery bypass grafting.
血栓形成是心脏手术患者潜在的危及生命的并发症。各种临床和遗传性疾病，如癌症、创伤、制动、存在因子V莱顿或凝血酶原20210A、蛋白C、S抑制剂或抗凝血酶缺乏或抵抗、凝血蛋白水平升高、抗磷脂抗体综合征、妊娠以及使用外源性激素等，都可能导致灾难性血栓形成。真性红细胞增多症（PV）患者会出现伴有脑血管和心血管事件的大量血栓。然而，心腔内血栓形成极为罕见。我们报告一例冠状动脉旁路移植术患者发生大量心内血栓形成的病例。
