Weiler R
Neurosci Lett. 1985 Mar 22;55(1):11-6. doi: 10.1016/0304-3940(85)90304-0.
Using immunocytochemical methods it was possible to demonstrate a small number of fibers within the optic nerve of the turtle Pseudemys scripta elegans exhibiting Met-enkephalin-like immunoreactivity. The fibers project to the retina where they ramify within the inner plexiform layer in the region of the visual streak. Retrograde labelling with Nuclear Yellow in combination with immunocytochemical staining revealed the origin of these fibers within visceral nuclei of the caudal mesencephalon. The existence of a mesencephalic, enkephalinergic pathway to the retina will facilitate further studies of opiate action in the retina by offering the possibility of selectively stimulating the endogenous release.
运用免疫细胞化学方法，在秀丽锦龟的视神经中发现了少量呈现甲硫氨酸脑啡肽样免疫反应性的纤维。这些纤维投射至视网膜，并在视觉带区域的内网状层分支。用核黄逆行标记并结合免疫细胞化学染色揭示了这些纤维起源于中脑尾部的内脏核。存在一条从中脑到视网膜的脑啡肽能通路，这将为选择性刺激内源性释放提供可能性，从而有助于进一步研究阿片类药物在视网膜中的作用。
