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影响儿童流感疫苗延迟接种:短信提醒的随机对照试验

Impacting delayed pediatric influenza vaccination: a randomized controlled trial of text message reminders.

作者信息

Hofstetter Annika M, Vargas Celibell Y, Camargo Stewin, Holleran Stephen, Vawdrey David K, Kharbanda Elyse Olshen, Stockwell Melissa S

机构信息

Department of Pediatrics, Columbia University; NewYork-Presbyterian Hospital, New York, New York.

Department of Pediatrics, Columbia University.

出版信息

Am J Prev Med. 2015 Apr;48(4):392-401. doi: 10.1016/j.amepre.2014.10.023.

DOI:10.1016/j.amepre.2014.10.023
PMID:25812465
Abstract

BACKGROUND

Influenza vaccination coverage is low, especially among low-income populations. Most doses are generally administered early in the influenza season, yet sustained vaccination efforts are crucial for achieving optimal coverage. The impact of text message influenza vaccination reminders was recently demonstrated in a low-income population. Little is known about their effect on children with delayed influenza vaccination or the most effective message type.

PURPOSE

To determine the impact of educational plus interactive text message reminders on influenza vaccination of urban low-income children unvaccinated by late fall.

DESIGN

Randomized controlled trial.

SETTING/PARTICIPANTS: Parents of 5,462 children aged 6 months-17 years from four academically affiliated pediatric clinics who were unvaccinated by mid-November 2011.

INTERVENTION

Eligible parents were stratified by their child's age and pediatric clinic site and randomized using a 1:1:1 allocation to educational plus interactive text message reminders, educational-only text message reminders, or usual care. Using an immunization registry-linked text messaging system, parents of intervention children received up to seven weekly text message reminders. One of the messages sent to parents in the educational plus interactive text message arm allowed selection of more information about influenza and influenza vaccination.

MAIN OUTCOME MEASURES

Influenza vaccination by March 31, 2012. Data were collected and analyzed between 2012 and 2014.

RESULTS

Most children were publicly insured and Spanish speaking. Baseline demographics were similar between groups. More children of parents in the educational plus interactive text message arm were vaccinated (38.5%) versus those in the educational-only text message (35.3%; difference=3.3%, 95% CI=0.02%, 6.5%; relative risk ratio (RRR)=1.09, 95% CI=1.002, 1.19) and usual care (34.8%; difference=3.8%, 95% CI=0.6%, 7.0%; RRR=1.11, 95% CI=1.02-1.21) arms.

CONCLUSIONS

Text message reminders with embedded educational information and options for interactivity have a small positive effect on influenza vaccination of urban, low-income, minority children who remain unvaccinated by late fall.

摘要

背景

流感疫苗接种率较低,尤其是在低收入人群中。大多数疫苗剂量通常在流感季节早期接种,但持续的疫苗接种工作对于实现最佳接种率至关重要。短信流感疫苗接种提醒的影响最近在低收入人群中得到了证实。对于它们对流感疫苗接种延迟的儿童的影响或最有效的信息类型知之甚少。

目的

确定教育加互动短信提醒对秋季末仍未接种疫苗的城市低收入儿童流感疫苗接种的影响。

设计

随机对照试验。

设置/参与者:来自四家学术附属儿科诊所的5462名6个月至17岁儿童的父母,这些儿童在2011年11月中旬仍未接种疫苗。

干预措施

符合条件的父母按其孩子的年龄和儿科诊所地点进行分层,并以1:1:1的比例随机分配到教育加互动短信提醒组、仅教育短信提醒组或常规护理组。使用与免疫登记相关的短信系统,干预组儿童的父母每周最多收到七条短信提醒。发送给教育加互动短信组父母的其中一条信息允许选择更多关于流感和流感疫苗接种的信息。

主要观察指标

截至2012年3月31日的流感疫苗接种情况。数据在2012年至2014年期间收集和分析。

结果

大多数儿童有公共保险且说西班牙语。各组之间的基线人口统计学特征相似。教育加互动短信组父母的孩子中接种疫苗的比例更高(38.5%),而仅教育短信组为(35.3%;差异=3.3%,95%可信区间=0.02%,6.5%;相对风险比(RRR)=1.09,95%可信区间=1.002,1.19),常规护理组为(34.8%;差异=3.8%,95%可信区间=0.6%,7.0%;RRR=1.11,95%可信区间=1.02 - 1.21)。

结论

带有嵌入式教育信息和互动选项的短信提醒对秋季末仍未接种疫苗的城市低收入少数族裔儿童的流感疫苗接种有微小的积极影响。

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