Luckenbach G A
Wien Klin Wochenschr. 1985 Mar 1;97(5):253-4.
The applicability of monoclonal antibodies (MAb) to the serological diagnosis of solid tumours is discussed. So far test kits with MAb cannot claim higher resolution of specificity as compared with conventional antisera. One approach to solve this problem would be to produce MAb to peptides derived from tumour extracts which are unique to malignant tissue.
讨论了单克隆抗体(MAb)在实体瘤血清学诊断中的适用性。到目前为止,与传统抗血清相比,含有单克隆抗体的检测试剂盒在特异性分辨率方面并无更高优势。解决这一问题的一种方法是制备针对源自肿瘤提取物的肽段的单克隆抗体,这些肽段是恶性组织所特有的。