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Does the difference between PART and Alzheimer's disease lie in the age-related changes in cerebral arteries that trigger the accumulation of Aβ and propagation of tau?

作者信息

Weller Roy O, Hawkes Cheryl A, Carare Roxana O, Hardy John

机构信息

Neuropathology, Clinical and Experimental Sciences, Faculty of Medicine, Institute for Life Sciences, Southampton University Hospital, University of Southampton, Mail Point 806, Southampton, SO16 6YD, UK,

出版信息

Acta Neuropathol. 2015 May;129(5):763-6. doi: 10.1007/s00401-015-1416-1. Epub 2015 Mar 27.

DOI:10.1007/s00401-015-1416-1
PMID:25814152
Abstract
摘要

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Does the difference between PART and Alzheimer's disease lie in the age-related changes in cerebral arteries that trigger the accumulation of Aβ and propagation of tau?PART与阿尔茨海默病之间的差异是否在于引发β淀粉样蛋白(Aβ)积累和tau蛋白扩散的脑动脉中与年龄相关的变化?
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PART, a distinct tauopathy, different from classical sporadic Alzheimer disease.PART,一种独特的tau蛋白病,与经典的散发性阿尔茨海默病不同。
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