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体外循环后高淀粉酶血症与胰腺炎的前瞻性研究。

A prospective study of hyperamylasemia and pancreatitis after cardiopulmonary bypass.

作者信息

Svensson L G, Decker G, Kinsley R B

出版信息

Ann Thorac Surg. 1985 May;39(5):409-11. doi: 10.1016/s0003-4975(10)61945-5.

DOI:10.1016/s0003-4975(10)61945-5
PMID:2581520
Abstract

General surgical complications after cardiopulmonary bypass (CPB) are infrequent but serious. No prospective studies have evaluated their incidence. We analyzed in such a study 135 patients who were to undergo CPB. Among these 135 patients, an abdominal complication developed in 6.6%; it contributed to 2 of the 5 deaths. Postoperative hyperamylasemia was found in 36% of patients, but only 2 had overt pancreatitis. The hyperamylasemia was not due to the salivary component, pulmonary complications, or prolonged CPB (r = 0.22). A gastrointestinal hemorrhage occurred in 7 patients. No patients had acute cholecystitis. We conclude that abdominal complications are more frequent than reported in retrospective studies, and result in significant morbidity and mortality. Postoperative hyperamylasemia is common but usually is not associated with untoward morbidity or mortality.

摘要

体外循环(CPB)后的普通外科并发症虽不常见但很严重。尚无前瞻性研究评估其发生率。在这样一项研究中,我们分析了135例拟接受CPB的患者。在这135例患者中,6.6%出现了腹部并发症;这导致了5例死亡中的2例。36%的患者术后出现高淀粉酶血症,但只有2例有明显的胰腺炎。高淀粉酶血症并非由唾液成分、肺部并发症或CPB时间延长所致(r = 0.22)。7例患者发生了胃肠道出血。无患者发生急性胆囊炎。我们得出结论,腹部并发症比回顾性研究所报告的更为常见,并导致显著的发病率和死亡率。术后高淀粉酶血症很常见,但通常与不良的发病率或死亡率无关。

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