Tang T T, Harb J M, Grossberg S E, Sedmak G V, Murphy J V
Arch Pathol Lab Med. 1985 Jun;109(6):543-5.
Tubuloreticular inclusions (TRI) have been observed in the rough endoplasmic reticulum of blood lymphocytes and monocytes in two cases of Reye's syndrome initiated by influenza infections. Tubuloreticular inclusions are seen in these mononuclear leukocytes during the acute phase of illness, but not during convalescence. Since TRI have been demonstrated in peripheral mononuclear leukocytes in patients with acquired immunodeficiency syndrome, systemic lupus erythematosus, and certain viral infections including T-cell leukemia, it may be that the finding of TRI in Reye's syndrome reflects a viral infection and/or immune dysfunction, if such association is not proved to be fortuitous.
在两例由流感感染引发的瑞氏综合征患者中，已在血液淋巴细胞和单核细胞的粗面内质网中观察到管状网状包涵体（TRI）。在疾病急性期，这些单核白细胞中可见管状网状包涵体，但在恢复期则未见。由于在获得性免疫缺陷综合征、系统性红斑狼疮以及包括T细胞白血病在内的某些病毒感染患者的外周单核白细胞中已证实存在TRI，因此在瑞氏综合征中发现TRI可能反映了病毒感染和/或免疫功能障碍，前提是这种关联未被证明是偶然的。
