Fuller G N, Jacobs J M
Department of Neuropathology, Institute of Neurology, Queen Square, London, Great Britain.
Acta Neuropathol. 1989;79(3):336-9. doi: 10.1007/BF00294672.
We report finding tubuloreticular inclusions (TRI) in the endothelial cells of endo- and epineurial vessels in the sural nerve of 11 patients with AIDS. Six patients had a painful peripheral neuropathy, one a non-painful sensory neuropathy, one an acute inflammatory demyelinating polyradiculoneuropathy and one a thalidomide-related neuropathy. Two patients had no clinical evidence of neuropathy. The TRI are not specific to one neuropathy and are unlikely to contribute to the pathogenesis of peripheral nerve syndromes in AIDS.
我们报告了在11例艾滋病患者的腓肠神经的内膜和神经束膜血管内皮细胞中发现了管网状包涵体（TRI）。6例患者患有疼痛性周围神经病变，1例患有非疼痛性感觉神经病变，1例患有急性炎症性脱髓鞘性多发性神经根神经病，1例患有沙利度胺相关性神经病变。2例患者没有周围神经病变的临床证据。TRI并非某一种神经病变所特有，也不太可能在艾滋病患者周围神经综合征的发病机制中起作用。
