碱性和酸性合成多肽对口腔细菌变形链球菌和血链球菌黏附于羟基磷灰石的影响。
The effects of basic and acidic synthetic polypeptides on the adherence of the oral bacteria, Streptococcus mutans and Streptococcus sanguis, to hydroxyapatite.
作者信息
Lamberts B L, Pederson E D, Simonson L G
出版信息
Arch Oral Biol. 1985;30(3):295-8. doi: 10.1016/0003-9969(85)90048-2.
PMID:2581534
Abstract
Two basic and two acidic synthetic polypeptides that bind strongly to hydroxyapatite at neutral pH were tested to determine their influence on adsorption of two Streptococcus mutans and two Streptococcus sanguis strains to hydroxyapatite. The adsorption of the strains was significantly enhanced or reduced by the basic and acidic agents, respectively. Study of acidic polypeptides provided evidence of competition between the polypeptides and the bacterial cells for hydroxyapatite adsorption sites.
摘要
测试了两种在中性pH下能与羟基磷灰石强烈结合的碱性和两种酸性合成多肽，以确定它们对两种变形链球菌和两种血链球菌菌株吸附到羟基磷灰石上的影响。碱性和酸性试剂分别显著增强或降低了菌株的吸附。对酸性多肽的研究提供了多肽与细菌细胞竞争羟基磷灰石吸附位点的证据。
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