Department of Chronomics and Gerontology, Tokyo Women's Medical University , Tokyo , Japan .
Clin Exp Hypertens. 2015;37(5):426-32. doi: 10.3109/10641963.2015.1013114. Epub 2015 Mar 27.
The effect of mild depression on blood pressure (BP) was assessed in 116 Japanese (32-79 years). As compared to non-depressive (Geriatric Depression Scale, GDS-15 score <5) subjects, mild depressives (GDS-15 score: 1-15) had shorter sleep duration (p = 0.021), lower subjective quality of life (health: p = 0.016; life satisfaction: p < 0.001; and happiness: p < 0.001), and higher 7-d systolic BP (p < 0.05). "Masked non-dipping" (dipping on day 1, but non-dipping on at least 1 of the following 6 d) was more frequent among depressive than non-depressive normotensives (p = 0.008). Among-day BP variability may underlie cardiovascular disease accompanying a key component of psychological depression.
116 名日本成年人（32-79 岁）的轻度抑郁对血压（BP）的影响。与非抑郁者（老年抑郁量表，GDS-15 评分<5）相比，轻度抑郁者（GDS-15 评分：1-15）的睡眠时间更短（p=0.021），主观生活质量更低（健康：p=0.016；生活满意度：p<0.001；幸福感：p<0.001），7 天收缩压更高（p<0.05）。与非抑郁的正常血压者相比，抑郁的正常血压者中更常见“隐匿性非杓型”（第 1 天杓型，但至少 6 天中的 1 天非杓型）（p=0.008）。日间血压变异性可能是伴随心理抑郁关键组成部分的心血管疾病的基础。
