Denyer Jacqueline, Gibson Elaine
Senior Clinical Nurse Specialist, Epidermolysis Bullosa.
Br J Nurs. 2015;24(6):S38, S40-3. doi: 10.12968/bjon.2015.24.Sup6.S38.
This non-comparative study explored the benefits of a natural gelling fibre dressing in 10 children with epidermolysis bullosa (EB). The clinical challenge in managing these children is that they often present with recalcitrant wounds that are perpetuated by critical colonisation, presence of biofilms and infection. KytoCel® (Aspen Medical) is a highly absorbent dressing composed of natural, biodegradable acylated chitosan. These fibres bond with wound exudate to form a clear gel that locks in fluid absorbs pathogens and is conformable to the wound bed. It also has haemostatic properties. ( Dutta PK et al, 2004 ; Lee et al, 2009 ; Stephen Haynes et al, 2014 ). Factors considered were whether the dressing could aid healing, reduce bleeding, reduce bioburden, be atraumatic and comfortable during wear time and removal.
这项非对照研究探讨了一种天然凝胶纤维敷料对10名大疱性表皮松解症（EB）患儿的益处。治疗这些患儿面临的临床挑战在于，他们常常出现难以愈合的伤口，这些伤口因严重定植、生物膜形成和感染而持续存在。KytoCel®（阿斯彭医疗公司）是一种高吸水性敷料，由天然、可生物降解的酰化壳聚糖组成。这些纤维与伤口渗出液结合形成透明凝胶，可锁住液体、吸收病原体，且与伤口床贴合。它还具有止血特性。（Dutta PK等人，2004年；Lee等人，2009年；Stephen Haynes等人，2014年）。研究考虑的因素包括该敷料是否有助于伤口愈合、减少出血、减轻生物负荷、在佩戴和去除过程中无创伤且舒适。
