Kungurtseva E A, Popkova S M, Leschenko O Ya
Vestn Ross Akad Med Nauk. 2014(9-10):27-32. doi: 10.15690/vramn.v69i9-10.1128.
This review presents the current data on the human microbiome. In recent increase of erased and primary chronic forms of inflammatory diseases of the female genital organs is observed, in which the clinical manifestations are varied, but the symptoms are not so much related with the changes in the pelvic organs, but with abnormalities in other body systems, secondarily involved in the pathological process. Recent research proved mutual influence of intestinal, vaginal and nasopharyngeal biocenosis. Women with vaginal microbiota disorders often revealed intestinal dysbiosis and chronic diseases of ENT (Ear Nose Throat) organs, which in turn contributes to chronic inflammatory process of pelvic organs, failure of therapeutic interventions, reduced quality of life and increased risk of adverse pregnancy outcomes.
本综述介绍了有关人类微生物组的当前数据。最近观察到女性生殖器官炎症性疾病的慢性形式和原发性慢性形式有所增加,其临床表现多种多样,但症状与其说是与盆腔器官的变化有关,不如说是与其他继发参与病理过程的身体系统异常有关。最近的研究证明了肠道、阴道和鼻咽生物群落之间的相互影响。阴道微生物群紊乱的女性常表现出肠道生态失调和耳鼻喉器官的慢性疾病,这反过来又会导致盆腔器官的慢性炎症过程、治疗干预失败、生活质量下降以及不良妊娠结局风险增加。