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[人皮肤培养黑素瘤细胞中染色体异常的异质性]

[Heterogeneity of chromosomal abnormalities in cultured melanoma cells of human skin].

作者信息

Koliubaeva S N, Danilova A B, Baldueva I A, Krasnova O R, Viktorova N A, Kissel' A V, Timova A A

出版信息

Vopr Onkol. 2014;60(5):596-601.

Abstract

Karyotypes of 9 malignant melanoma patients has been described. It is ascertained that most often the damage is observed in chromosomes 1, 6, 7, 9 and 17, which is consistent with the data in the literature. Besides chromosomes 5 and 13 are also often involved in different rearrangements. Recurring aberrations are not discovered. Any correlation between survival and non-recurrent chromosomal aberrations is not discovered.

摘要

已描述了9例恶性黑色素瘤患者的核型。已确定,最常观察到的损伤发生在1、6、7、9和17号染色体上,这与文献中的数据一致。此外,5号和13号染色体也经常参与不同的重排。未发现复发性畸变。未发现生存与非复发性染色体畸变之间存在任何相关性。

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