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一维生物力学轨迹分析中的零维与一维、参数化与非参数化以及置信区间与假设检验程序

Zero- vs. one-dimensional, parametric vs. non-parametric, and confidence interval vs. hypothesis testing procedures in one-dimensional biomechanical trajectory analysis.

作者信息

Pataky Todd C, Vanrenterghem Jos, Robinson Mark A

机构信息

Department of Bioengineering, Shinshu University, Japan.

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, UK.

出版信息

J Biomech. 2015 May 1;48(7):1277-85. doi: 10.1016/j.jbiomech.2015.02.051. Epub 2015 Mar 13.

Abstract

Biomechanical processes are often manifested as one-dimensional (1D) trajectories. It has been shown that 1D confidence intervals (CIs) are biased when based on 0D statistical procedures, and the non-parametric 1D bootstrap CI has emerged in the Biomechanics literature as a viable solution. The primary purpose of this paper was to clarify that, for 1D biomechanics datasets, the distinction between 0D and 1D methods is much more important than the distinction between parametric and non-parametric procedures. A secondary purpose was to demonstrate that a parametric equivalent to the 1D bootstrap exists in the form of a random field theory (RFT) correction for multiple comparisons. To emphasize these points we analyzed six datasets consisting of force and kinematic trajectories in one-sample, paired, two-sample and regression designs. Results showed, first, that the 1D bootstrap and other 1D non-parametric CIs were qualitatively identical to RFT CIs, and all were very different from 0D CIs. Second, 1D parametric and 1D non-parametric hypothesis testing results were qualitatively identical for all six datasets. Last, we highlight the limitations of 1D CIs by demonstrating that they are complex, design-dependent, and thus non-generalizable. These results suggest that (i) analyses of 1D data based on 0D models of randomness are generally biased unless one explicitly identifies 0D variables before the experiment, and (ii) parametric and non-parametric 1D hypothesis testing provide an unambiguous framework for analysis when one׳s hypothesis explicitly or implicitly pertains to whole 1D trajectories.

摘要

生物力学过程通常表现为一维(1D)轨迹。研究表明,基于零维(0D)统计程序的一维置信区间(CI)存在偏差,非参数一维自助法CI已作为一种可行的解决方案出现在生物力学文献中。本文的主要目的是阐明,对于一维生物力学数据集,零维和一维方法之间的区别比参数和非参数程序之间的区别更为重要。第二个目的是证明,存在一种与一维自助法等效的参数方法,其形式为用于多重比较的随机场理论(RFT)校正。为了强调这些要点,我们分析了六个数据集,这些数据集包含单样本、配对、双样本和回归设计中的力和运动学轨迹。结果表明,首先,一维自助法和其他一维非参数CI在质量上与RFT CI相同,并且都与零维CI非常不同。其次,对于所有六个数据集,一维参数和一维非参数假设检验结果在质量上是相同的。最后,我们通过证明一维CI复杂、依赖设计且因此不可推广,突出了它们的局限性。这些结果表明:(i)基于零维随机性模型对一维数据进行分析通常存在偏差,除非在实验前明确识别零维变量;(ii)当一个人的假设明确或隐含地涉及整个一维轨迹时,参数和非参数一维假设检验提供了一个明确的分析框架。

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