Zhao HongMei, Lian YaJun
Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Australas J Dermatol. 2015 Aug;56(3):202-5. doi: 10.1111/ajd.12326. Epub 2015 Mar 29.
Raynaud's phenomenon is often accompanied by pain, digital ulceration and compromised daily activities. Pharmacological therapy or sympathectomies have been administered to diminish these symptoms but existing treatments are not invariably efficacious. A recent case series has described the use of botulinum toxin type A in the treatment of Raynaud's phenomenon. We report two patients with severe or mild Raynaud's phenomenon who were injected with BTX-A; both of whom experienced clinical and image improvement after treatment.
雷诺现象常伴有疼痛、手指溃疡及日常活动受限。以往采用药物治疗或交感神经切除术来减轻这些症状，但现有治疗方法并非总能奏效。最近有一系列病例报道了A型肉毒杆菌毒素用于治疗雷诺现象。我们报告了两名分别患有重度和轻度雷诺现象的患者接受了A型肉毒杆菌毒素注射治疗；两名患者在治疗后临床症状及影像学表现均有改善。
