额极皮质在工作记忆中整合信息操控方面的作用。
The role of the frontopolar cortex in manipulation of integrated information in working memory.
作者信息
Kim Chobok, Kroger James K, Calhoun Vince D, Clark Vincent P
机构信息
Department of Psychology, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 702-701, South Korea.
Department of Psychology, New Mexico State University, Las Cruces, NM, USA; Department of Psychology, University of New Mexico, Albuquerque, NM, USA.
出版信息
Neurosci Lett. 2015 May 19;595:25-9. doi: 10.1016/j.neulet.2015.03.044. Epub 2015 Mar 25.
Abstract
Cognitive operations often require integration of information. Previous studies have shown that, integration of information in working memory recruits frontopolar cortex (FPC). In this fMRI study, we sought to reveal neural mechanisms of FPC underlying the integration of information during arithmetic tasks. We compared a condition requiring manipulation of two features of an item held in working memory with manipulation of one feature. The results showed that, FPC was equally recruited in both conditions, while dorsolateral prefrontal cortex (DLPFC) tended to be more activated when manipulating two features. We suggest that, FPC plays an integrative role and is recruited by the production of representations in accordance with task constraints, whereas DLPFC appears to be sensitive to processing demands induced by the manipulation of information.
摘要
认知操作通常需要信息整合。先前的研究表明，工作记忆中的信息整合会激活额极皮层（FPC）。在这项功能磁共振成像（fMRI）研究中，我们试图揭示在算术任务期间FPC进行信息整合的神经机制。我们比较了一种需要对工作记忆中保存的项目的两个特征进行操作的情况与对一个特征进行操作的情况。结果表明，在两种情况下FPC的激活程度相同，而在操作两个特征时背外侧前额叶皮层（DLPFC）的激活程度往往更高。我们认为，FPC发挥着整合作用，并且根据任务限制通过表征的产生而被激活，而DLPFC似乎对信息操作所引发的加工需求敏感。
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