Department of Cognitive Neuroscience and Neuroergonomics, Institute of Applied Psychology, Jagiellonian University, Lojasiewicza Street 4, 30-348, Krakow, Poland.
Department of Psychology, University of Wisconsin-Oshkosh, Oshkosh, WI, USA.
Sci Rep. 2023 Feb 18;13(1):2900. doi: 10.1038/s41598-023-29869-2.
Human memory is prone to errors in many everyday activities but also when cultivating hobbies such as traveling and/or learning a new language. For instance, while visiting foreign countries, people erroneously recall foreign language words that are meaningless to them. Our research simulated such errors in a modified Deese-Roediger-McDermott paradigm for short-term memory with phonologically related stimuli aimed at uncovering behavioral and neuronal indices of false memory formation with regard to time-of-day, a variable known to influence memory. Fifty-eight participants were tested in a magnetic resonance (MR) scanner twice. The results of an Independent Component Analysis revealed encoding-related activity of the medial visual network preceding correct recognition of positive probes and correct rejection of lure probes. The engagement of this network preceding false alarms was not observed. We also explored if diurnal rhythmicity influences working memory processes. Diurnal differences were seen in the default mode network and the medial visual network with lower deactivation in the evening hours. The GLM results showed greater activation of the right lingual gyrus, part of the visual cortex and the left cerebellum in the evening. The study offers new insight into the mechanisms associated with false memories, suggesting that deficient engagement of the medial visual network during the memorization phase of a task results in short-term memory distortions. The results shed new light on the dynamics of working memory processes by taking into account the effect of time-of-day on memory performance.
人类的记忆在许多日常活动中容易出错，在培养旅行和/或学习新语言等爱好时也是如此。例如，在访问外国时，人们会错误地回忆起对他们来说毫无意义的外语单词。我们的研究在短期记忆的改良的 Deese-Roediger-McDermott 范式中模拟了这种错误，使用了与语音相关的刺激物，旨在揭示与时间相关的错误记忆形成的行为和神经指标，时间是已知会影响记忆的变量。58 名参与者在磁共振（MR）扫描仪中接受了两次测试。独立成分分析的结果显示，在正确识别正探针和正确拒绝诱饵探针之前，内侧视觉网络的编码相关活动。在错误警报之前没有观察到该网络的参与。我们还探讨了昼夜节律是否会影响工作记忆过程。在默认模式网络和内侧视觉网络中观察到昼夜差异，傍晚时的去激活程度较低。GLM 结果显示，傍晚时右侧舌回、部分视觉皮层和左侧小脑的激活程度更大。该研究提供了对与错误记忆相关的机制的新见解，表明在任务的记忆阶段内侧视觉网络参与不足会导致短期记忆扭曲。该结果通过考虑时间对记忆表现的影响，为工作记忆过程的动态提供了新的认识。
