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[白血病患者与非血液系统疾病患者骨髓的体外研究]

[In vitro study of bone marrow from leukemia patients and patients without hematologic disease].

作者信息

Varga G, Borbényi Z, Krizsa F, Cserháti I

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1985;112(1):125-33.

PMID:2581857
Abstract

The bone-marrow of 26 patients not affected with hematological diseases and 10 patients with untreated leukemia was investigated according to Dexter in long-term cultures. Survival time and cell content of those long-term cultures started with normal bone marrow were not influenced significantly, if reinoculation was made with autologeneic or allogeneic bone marrow. Even without repeated inoculation, leukemic cells grew for a longer time in long-term cultures than normal bone marrow cells. As far as the outcome of the disease is concerned, no conclusion can be drawn from the duration of cultivating leukemic cells growth.

摘要

根据德克斯特方法,对26例未患血液系统疾病的患者及10例未经治疗的白血病患者的骨髓进行了长期培养研究。如果用自体或异体骨髓进行再次接种,起始于正常骨髓的那些长期培养物的存活时间和细胞含量未受到显著影响。即使不进行重复接种,白血病细胞在长期培养中生长的时间也比正常骨髓细胞长。就疾病的转归而言,从白血病细胞生长的培养持续时间无法得出结论。

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