Meng Hailiang, Fang Xiangyi, Hao Dingjun, Wang Weidong
Department of Spine Surgery, Red Cross Hospital Affiliated to Xi'an Jiaotong University, Xi'an 710054,
Nan Fang Yi Ke Da Xue Xue Bao. 2015 Mar;35(3):315-8.
To investigate the incidence of C5 nerve root palsy after multi-segmental cervical decompression through different approaches.
This study was conducted among 375 patients undergoing multi-segmental cervical decompression in anterior corpectomy and fusion fixation, anterior cervical corpectomy and fusion fixation + posterior decompression and fusion fixation, posterior cervical laminectomy decompression, fusion and internal fixation, and posterior laminoplasty and fusion groups. The exclusion criteria included lack of follow-up data, spinal cord injury preventing preoperative or postoperative motor testing, or surgery not involving the C5 level. The incidence of C5 palsy was determined and the potential risk factors C5 palsy were analyzed including age, sex, revision surgery, preoperative weakness, diabetes, smoking, number of levels decompressed, and a history of previous upper extremity surgery.
Of the 375 patients, 60 patients were excluded and the data of 315 patients were analyzed, including 146 women and 169 men with a mean age of 57.7 years (range 39-72 years). The overall incidence of C5 nerve palsy was 6.03% (19/315) in these patients; in the subgroups receiving different surgeries, the incidence was 8.62% in the cervical road laminectomy and fusion fixation group, 7.79% in the anterior cervical corpectomy and fusion fixation + posterior decompression and fusion and internal fixation, 4.68% in the anterior corpectomy and fusion fixation group, and 3.85% in the posterior laminoplasty and fusion group. No significant difference was found in the incidences among the subgroups, but men were more likely than women to develop cervical nerve root palsy (8.28% vs 3.42%, P<0.05).
The overall incidence of C5 nerve palsy following postoperative cervical spinal decompression was 6.03% in our cohort. The incidence of C5 nerve palsy did not differ significantly following different cervical decompression surgeries, but the incidence was the highest in the posterior cervical laminectomy and fusion and internal fixation group.
探讨不同手术入路多节段颈椎减压术后C5神经根麻痹的发生率。
本研究纳入375例行多节段颈椎减压术的患者,术式包括前路椎体次全切除融合内固定术、前路椎体次全切除融合内固定术+后路减压融合内固定术、后路颈椎椎板切除减压融合内固定术及后路单开门椎管扩大成形融合术。排除标准包括缺乏随访数据、脊髓损伤导致术前或术后无法进行运动功能测试,或手术未涉及C5节段。确定C5麻痹的发生率,并分析C5麻痹的潜在危险因素,包括年龄、性别、翻修手术、术前肌无力、糖尿病、吸烟、减压节段数及既往上肢手术史。
375例患者中,60例被排除,对315例患者的数据进行分析,其中女性146例,男性169例,平均年龄57.7岁(39 - 72岁)。这些患者中C5神经麻痹的总体发生率为6.03%(19/315);在接受不同手术的亚组中,后路颈椎椎板切除融合内固定组的发生率为8.62%,前路椎体次全切除融合内固定术+后路减压融合内固定组为7.79%,前路椎体次全切除融合内固定组为4.68%,后路单开门椎管扩大成形融合组为3.85%。亚组间发生率无显著差异,但男性发生颈神经根麻痹的可能性高于女性(8.28%对3.42%,P<0.05)。
在我们的队列中,颈椎减压术后C5神经麻痹的总体发生率为6.03%。不同颈椎减压手术后C5神经麻痹的发生率无显著差异,但后路颈椎椎板切除融合内固定组的发生率最高。