Sölter J, Uhlenbruck G, Düvel H, Raftery B, Mohr R
Immunobiology. 1985 Apr;169(3):330-4. doi: 10.1016/s0171-2985(85)80044-9.
Using the hybridoma technique, a series of four monoclonal antibodies to the galactan isolated from albumin glands of wine yard snails (Helix pomatia) could be generated. Characterization of the binding properties of one of these antibodies revealed a specificity for beta-(1,6)-glycosidically linked D-galactose residues. This could be demonstrated by reaction of the antibody with beta-(1,6)-D-galactans and by the D-galactose-inhibitable binding to group B streptococci of type II, which possess beta-(1,6)-linked D-galactose as immuno-determinant group.
利用杂交瘤技术，可以产生一系列针对从葡萄园蜗牛（Helix pomatia）白蛋白腺中分离出的半乳聚糖的四种单克隆抗体。对其中一种抗体的结合特性进行表征后发现，它对β-(1,6)-糖苷键连接的D-半乳糖残基具有特异性。这可以通过该抗体与β-(1,6)-D-半乳聚糖的反应以及与具有β-(1,6)-连接的D-半乳糖作为免疫决定簇的II型B组链球菌的D-半乳糖抑制性结合来证明。
