Saltzman Amanda F, Gills Jessie R R, LeBlanc Dana M, Velez Maria C, Craver Randall D, Roth Christopher C
Department of Urology, Louisiana State University Health Sciences Center, New Orleans, LA.
Department of Hematology/Oncology, Children's Hospital of New Orleans, New Orleans, LA.
Urology. 2015 May;85(5):1186-1189. doi: 10.1016/j.urology.2015.01.034. Epub 2015 Mar 25.
Even though vaginal bleeding is an unusual clinical presentation in infants and young children, thorough evaluation by the pediatric urologist requires the recognition and knowledge of less-common conditions, including malignancy. Extragonadal germ cell tumors are rare in children aged <15 years, representing approximately 1% of all cancers. Because of the close collaboration between pediatric oncologists and pediatric urologists, a multidisciplinary approach to the management and treatment of these tumors includes chemotherapy and surgical resection, aiming for fertility preservation when possible. We present a 10-month-old infant with a cervical or uterine germ cell tumor and the challenges found during her treatment.
尽管阴道出血在婴幼儿中是一种不常见的临床表现,但小儿泌尿科医生进行全面评估需要识别和了解包括恶性肿瘤在内的罕见病症。性腺外生殖细胞肿瘤在15岁以下儿童中很少见,约占所有癌症的1%。由于小儿肿瘤学家和小儿泌尿科医生之间的密切合作,对这些肿瘤的管理和治疗采用多学科方法,包括化疗和手术切除,尽可能保留生育能力。我们报告一名10个月大的婴儿患有宫颈或子宫生殖细胞肿瘤以及在其治疗过程中发现的挑战。