Radiology Department, Royal Brompton Hospital, Sydney Street, London SW3 6NP, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
National Heart and Lung Institute, Imperial College London, London, United Kingdom; Cardiac Electrophysiology Department, Royal Brompton Hospital, London, United Kingdom.
J Cardiovasc Comput Tomogr. 2015 Mar-Apr;9(2):89-102. doi: 10.1016/j.jcct.2015.01.011. Epub 2015 Jan 24.
Cardioembolic stroke is an important complication of atrial fibrillation. The thrombus responsible for this arises from the left atrial appendage (LAA) in >90% of cases, providing the rationale for device-based LAA closure as a means of thromboprophylaxis. Although oral anticoagulant therapy remains the mainstay for reducing the risk of stroke in patients with atrial fibrillation, an increasing number of patients, particularly those ineligible for conventional pharmacotherapy, are being offered percutaneous left atrial appendage closure. Cardiovascular CT can provide important information to assess the suitability of patients for LAA interventions and guide device selection and approach. The high spatial resolution and multiplanar capability of contemporary contrast-enhanced gated multidetector cardiovascular CT render it an ideal modality for noninvasively evaluating patients before intervention and assessing patients after intervention both for complications and procedural outcome.
心源性脑卒是心房颤动的一个重要并发症。有超过 90%的病例血栓源于左心耳(LAA),这为器械性 LAA 封堵作为一种血栓预防手段提供了理论依据。尽管口服抗凝治疗仍然是降低心房颤动患者卒中风险的主要方法,但越来越多的患者,特别是那些不适合传统药物治疗的患者,正在接受经皮左心耳封堵术。心血管 CT 可以提供重要信息,以评估患者接受 LAA 干预的适宜性,并指导器械选择和方法。现代增强门控多排心血管 CT 的高空间分辨率和多平面能力使其成为一种理想的非侵入性方法,可在介入前评估患者,并在介入后评估患者的并发症和手术结果。