Department of Osteopathic Medical Specialties, Michigan State University College of Osteopathic Medicine, East Lansing.
Department of Osteopathic Medical Specialties, Michigan State University College of Osteopathic Medicine, East Lansing.
Am J Med. 2015 Aug;128(8):844-51. doi: 10.1016/j.amjmed.2015.03.007. Epub 2015 Mar 27.
As with many uncommon diseases, data in patients with pulmonary arterial hypertension are sparse in regard to emergency service visits, hospitalizations, and mortality. The purpose of this investigation is to assess the scope of the problem of Group 1 pulmonary arterial hypertension in adults in the US and trends from 2001 to 2007.
The Nationwide Emergency Department Sample, 2007-2011, was used to determine the number of emergency department visits, hospitalizations, and all-cause mortality of patients aged ≥18 years with Group 1 pulmonary arterial hypertension. We assessed patients with a discharge code for "primary pulmonary hypertension," and excluded patients with known causes of pulmonary hypertension that are not classified as Group 1.
There were 64,451 emergency department visits and 52,779 hospitalizations for pulmonary arterial hypertension from 2007-2011 in patients aged ≥18 years. The proportion of all emergency department visits that were for pulmonary arterial hypertension decreased from 16.4/100,000 visits in 2007 to 8.9/100,000 visits in 2011 (P < .0001). The proportion of all hospitalizations that were for pulmonary arterial hypertension decreased from 79/100,000 hospitalizations in 2007 to 38/100,000 hospitalizations in 2011 (P < .0001). Population-based death rates in patients with pulmonary arterial hypertension decreased from 4.6/million population in 2007 to 1.7/million population in 2011 (P < .0001).
Decreasing rates of emergency department visits, hospitalizations, and deaths in patients with Group 1 pulmonary arterial hypertension were shown from 2007-2011. We speculate that this resulted from improved treatment during the period of observation.
与许多罕见疾病一样，有关肺动脉高压患者的急诊就诊、住院和死亡率的数据很少。本研究旨在评估美国成人 1 型肺动脉高压患者的问题范围，并分析 2001 年至 2007 年的趋势。
使用 2007-2011 年全国急诊部样本确定年龄≥18 岁的 1 型肺动脉高压患者的急诊就诊、住院和全因死亡率。我们评估了有“原发性肺动脉高压”出院代码的患者，并排除了不属于 1 型的已知肺动脉高压病因的患者。
2007-2011 年，年龄≥18 岁的患者中有 64451 次急诊就诊和 52779 次肺动脉高压住院治疗。所有急诊就诊中因肺动脉高压就诊的比例从 2007 年的 16.4/100000 次就诊降至 2011 年的 8.9/100000 次就诊（P<0.0001）。所有住院患者中因肺动脉高压住院的比例从 2007 年的 79/100000 次住院降至 2011 年的 38/100000 次住院（P<0.0001）。肺动脉高压患者的人群死亡率从 2007 年的 4.6/百万人口降至 2011 年的 1.7/百万人口（P<0.0001）。
从 2007 年至 2011 年，1 型肺动脉高压患者的急诊就诊、住院和死亡人数呈下降趋势。我们推测这是由于观察期间治疗的改善所致。
