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钙乳症结石:影像学表现及治疗结果

Milk of calcium stones: radiological signs and management outcome.

作者信息

El-Shazly M

机构信息

Urology Department, Menoufia University, Shebin El-Kom, Egypt,

出版信息

Urolithiasis. 2015 Jun;43(3):221-5. doi: 10.1007/s00240-015-0767-3. Epub 2015 Mar 29.

DOI:10.1007/s00240-015-0767-3
PMID:25820293
Abstract

Milk of calcium (MOC) is a rare type of stone that was first described in 1940 by Ludin and Howald who reported MOC in renal cysts. Milk of calcium is a viscous colloidal suspension of calcium salts. Stasis, obstruction and infection are important predisposing factors. Due to a layering effect, characteristic radiological signs especially in CT can help in diagnosis to avoid unsuccessful shock wave lithotripsy. This is the largest reported case series, in which radiological signs by CT scan to predict renal MOC stones, clinical picture and management outcome are described in detail. Cases with suspected renal milk of calcium stones were studied over 7 years (2008-2015). All cases were diagnosed preoperatively by non-contrast CT. Urine cultures were performed in all patients preoperatively. Intra-operative and postoperative findings were reported. Stones retrieved were sent for chemical analysis using an infrared method. Seven cases of milk of calcium renal stones were included in this study. These stones were faint radio-opaque in two cases and radiolucent in five cases. All cases were diagnosed preoperatively with non-contrast CT. Their Hounsfield units (HU) ranged from 114 to 612. All stones were located in a dependent position (gravitational effect) in the posterior aspect of dilated calyces. Five cases exhibited the typical fluid level and two cases demonstrated semilunar (half moon) pattern in the anterior surface of the stones. All cases underwent PCNL with suction and retrieval of soft stones without the need for disintegration. When stones demonstrate a low Hounsfield unit, are arranged in dependent positions within dilated calyces and exhibit fluid level or semilunar pattern on non-contrast CT, milk of calcium stones should be considered. PCNL is an effective modality for management of renal milk of calcium stones.

摘要

钙乳症(MOC)是一种罕见的结石类型,1940年由卢丁和霍瓦尔德首次描述,他们报告了肾囊肿中的钙乳症。钙乳是钙盐的粘性胶体悬浮液。淤滞、梗阻和感染是重要的诱发因素。由于分层效应,特征性的放射学征象,尤其是在CT上,有助于诊断,以避免冲击波碎石术失败。这是报道的最大病例系列,其中详细描述了通过CT扫描预测肾钙乳症结石的放射学征象、临床表现和治疗结果。对疑似肾钙乳症结石的病例进行了7年(2008 - 2015年)的研究。所有病例术前均通过非增强CT诊断。所有患者术前均进行了尿培养。报告了术中及术后的发现。取出的结石采用红外方法进行化学分析。本研究纳入了7例肾钙乳症结石病例。这些结石中有2例呈淡放射性不透光,5例呈放射性透光。所有病例术前均通过非增强CT诊断。其亨氏单位(HU)范围为114至612。所有结石均位于扩张肾盏后侧的下垂位置(重力作用)。5例呈现典型的液平,2例在结石前表面显示半月形(半月)模式。所有病例均接受了经皮肾镜取石术(PCNL),通过吸引取出软性结石,无需碎石。当结石在非增强CT上显示亨氏单位较低、位于扩张肾盏内的下垂位置且呈现液平或半月形模式时,应考虑钙乳症结石。PCNL是治疗肾钙乳症结石的有效方法。

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Rapidly developing renal milk of calcium in a patient with myelomonocytic leukaemia.一名骨髓单核细胞白血病患者快速形成肾钙乳症。
JRSM Open. 2014 Jun 9;5(7):2054270414533324. doi: 10.1177/2054270414533324. eCollection 2014 Jul.
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Milk of calcium (MOC) cysts masquerading as renal calculi - a trap for the unwary.伪装成肾结石的钙乳(MOC)囊肿——粗心者的陷阱。
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Milk of calcium in abdomen.腹部积乳。
Urology. 2011 Mar;77(3):596-7. doi: 10.1016/j.urology.2010.03.056. Epub 2010 Aug 13.
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Milk of calcium collection in the differential diagnosis of giant renal calculus.巨大肾结石鉴别诊断中的钙乳症聚集
Br J Radiol. 2008 Feb;81(962):e35-6. doi: 10.1259/bjr/26082288.
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Renal milk of calcium: contraindication to extracorporeal shockwave lithotripsy.肾钙乳:体外冲击波碎石术的禁忌证。
Tech Urol. 1996 Summer;2(2):102-7.
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