Scerri Erica Sultana, McDonald Fraser, Camilleri Simon
*Department of Dental Surgery, Mater Dei Hospital, Tal-Qroqq, Msida, Malta.
**Department of Orthodontics, King's College London Dental Institute, London, UK.
Eur J Orthod. 2016 Feb;38(1):79-84. doi: 10.1093/ejo/cjv014. Epub 2015 Mar 28.
To compare the developmental dental anomalies associated with maxillary canine-first premolar (MxCP1) transposition and those of palatally displaced canine (PDC) with each other and with the background prevalence in the Maltese population in order to elucidate whether the two conditions have similar or differing genetic backgrounds.
Dental records of 477 subjects with PDC, 57 subjects with MxCP1, and a control group of 500 subjects with no history of a PDC or tooth transposition were compared for canine eruption anomalies and hypodontia.
A high frequency of bilateral occurrence was present for both canine malpositions and when unilateral, a trend to right-sided occurrence was evident. The occurrence of transpositions in the PDC group and of PDC in the MxCP1 group was higher than expected. The prevalence of incisor hypodontia was significantly higher in subjects with PDC and MxCP1, as compared to the control group.
The size of the MxCP1 group is relatively small. The study population is a small isolated Caucasian population and the results may not be applicable to other populations.
There is no significant difference between the MxCP1 and PDC groups in the prevalence or distribution of hypodontia and each of these groups exhibits a higher prevalence of the other canine anomaly. These findings support the theory that PDC and MxCP1 form part of a group of interrelated dental anomalies that share a common genetic basis.
比较与上颌尖牙-第一前磨牙(MxCP1)易位相关的牙齿发育异常情况以及与腭侧异位尖牙(PDC)相关的牙齿发育异常情况,并与马耳他人群的背景患病率进行比较,以阐明这两种情况是否具有相似或不同的遗传背景。
比较了477例患有PDC的受试者、57例患有MxCP1的受试者以及500例无PDC或牙齿易位病史的对照组受试者的牙齿记录,以观察尖牙萌出异常和牙缺失情况。
两种尖牙错位情况均有较高的双侧发生率,单侧发生时,明显有右侧发生的趋势。PDC组中易位的发生率以及MxCP1组中PDC的发生率均高于预期。与对照组相比,PDC和MxCP1受试者中切牙缺失的患病率显著更高。
MxCP1组的样本量相对较小。研究人群是一个小型孤立的白种人群体,结果可能不适用于其他人群。
MxCP1组和PDC组在牙缺失的患病率或分布上没有显著差异,并且每组中另一种尖牙异常的患病率都更高。这些发现支持了以下理论,即PDC和MxCP1构成了一组具有共同遗传基础的相互关联的牙齿异常的一部分。