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通过血液中磷脂酰乙醇测量的酒精摄入量以及终生饮酒史访谈与银屑病的严重程度相关。

Alcohol intake measured by phosphatidylethanol in blood and the lifetime drinking history interview are correlated with the extent of psoriasis.

作者信息

Zou Linnea, Lonne-Rahm Sol-Britt, Helander Anders, Stokkeland Knut, Franck Johan, Nordlind Klas

机构信息

Department of Dermatology and Venereology, Södersjukhuset, Stockholm, Sweden.

出版信息

Dermatology. 2015;230(4):375-80. doi: 10.1159/000380818. Epub 2015 Mar 21.

Abstract

BACKGROUND

Psoriasis has been reported to be associated with alcohol consumption.

OBJECTIVE

To investigate the level of alcohol intake in individuals with psoriasis and correlate intake with the extent of disease and pruritus.

METHODS

Twenty-nine outpatients (15 females and 14 males) with stable chronic plaque psoriasis of moderate severity were recruited. The Psoriasis Area and Severity Index (PASI) and the degree of pruritus (visual analogue scale) were compared with measures of drinking habits as determined by the Lifetime Drinking History (LDH), the Alcohol Use Disorders Identification Test and whole-blood phosphatidylethanol (PEth), an alcohol-specific biomarker.

RESULTS

The majority of patients were social drinkers with moderate alcohol consumption as determined by PEth and LDH. Alcohol consumption correlated significantly with the PASI score. There was no correlation between alcohol use and pruritus.

CONCLUSION

The level of alcohol consumption is correlated with the extent of psoriasis.

摘要

背景

据报道,银屑病与饮酒有关。

目的

调查银屑病患者的酒精摄入量,并将摄入量与疾病程度和瘙痒程度相关联。

方法

招募了29例中度严重程度的稳定慢性斑块状银屑病门诊患者(15名女性和14名男性)。将银屑病面积和严重程度指数(PASI)以及瘙痒程度(视觉模拟量表)与通过终生饮酒史(LDH)、酒精使用障碍识别测试和全血磷脂酰乙醇(PEth,一种酒精特异性生物标志物)确定的饮酒习惯测量值进行比较。

结果

根据PEth和LDH确定,大多数患者为社交饮酒者,酒精摄入量适中。酒精摄入量与PASI评分显著相关。饮酒与瘙痒之间无相关性。

结论

酒精消费水平与银屑病的严重程度相关。

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