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为住院阿片类药物依赖患者启动丁丙诺啡治疗:病例系列

Initiating buprenorphine treatment for hospitalized patients with opioid dependence: A case series.

作者信息

Suzuki Joji, DeVido Jeffrey, Kalra Inder, Mittal Leena, Shah Sejal, Zinser Jennifer, Weiss Roger D

机构信息

Department of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.

出版信息

Am J Addict. 2015 Jan;24(1):10-4. doi: 10.1111/ajad.12161.

DOI:10.1111/ajad.12161
PMID:25823630
Abstract

BACKGROUND AND OBJECTIVES

Opioid dependent patients are hospitalized frequently. We aimed to determine if initiation of buprenorphine treatment during hospitalization facilitates entry into treatment following discharge.

METHODS

Retrospective case series (n = 47).

RESULTS

Twenty-two (46.8%) patients successfully initiated buprenorphine treatment within 2 months of discharge. Those patients obtaining a referral to a specific program were more successful in continuing treatment, but this difference did not reach statistical significance (59.1% vs 39.1%, p = 0.18).

DISCUSSION AND CONCLUSIONS

Hospitalization may be an important opportunity to engage opioid dependent patients to initiate buprenorphine treatment.

SCIENTIFIC SIGNIFICANCE

This study provides provisional support for utilizing buprenorphine for hospitalized patients.

摘要

背景与目的

阿片类药物依赖患者经常住院。我们旨在确定住院期间开始丁丙诺啡治疗是否有助于出院后进入治疗。

方法

回顾性病例系列(n = 47)。

结果

22名(46.8%)患者在出院后2个月内成功开始丁丙诺啡治疗。那些获得转介到特定项目的患者在继续治疗方面更成功,但这种差异未达到统计学意义(59.1%对39.1%,p = 0.18)。

讨论与结论

住院可能是促使阿片类药物依赖患者开始丁丙诺啡治疗的重要时机。

科学意义

本研究为住院患者使用丁丙诺啡提供了初步支持。

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