ADHD 和 ASD 特质连续体的高、低极端是否代表适应不良的行为和认知结果？一项基于人群的研究。
Do High and Low Extremes of ADHD and ASD Trait Continua Represent Maladaptive Behavioral and Cognitive Outcomes? A Population-Based Study.
机构信息
1 Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Department of Cognitive Neuroscience, Nijmegen, The Netherlands.
2 Karakter Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands.
出版信息
J Atten Disord. 2018 Aug;22(10):924-932. doi: 10.1177/1087054715577136. Epub 2015 Mar 30.
OBJECTIVE
Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are thought to reflect the high, symptomatic extreme of quantitative trait continua. However, extreme deviations in either direction on disorder continua, high and low, may both represent maladaptive behavioral and cognitive outcomes. We aimed to test this hypothesis.
METHOD
In a population sample of 378 children, ADHD and ASD traits were rated by parents on questionnaires that provide resolution at high and low extremes of the ADHD and ASD trait continua. ADHD and ASD traits were related to parent-ratings of internalizing and externalizing behavior problems and tests of cognitive functioning using polynomial regression.
RESULTS
The low ends of the ADHD and ASD trait continua were related to fewer behavior problems and better cognitive functioning than symptomatic ends.
CONCLUSION
Studying the correlates of the low continuum ends may deepen our understanding of the mechanisms underlying adaptive behavioral and cognitive outcomes.
目的
注意缺陷多动障碍（ADHD）和自闭症谱系障碍（ASD）被认为反映了数量性状连续体的高、症状极端。然而，在障碍连续体的两个极端方向上的极端偏差，高和低，都可能代表适应不良的行为和认知结果。我们旨在检验这一假设。
方法
在一个 378 名儿童的人群样本中，ADHD 和 ASD 特征由父母在问卷上进行评定，这些问卷在 ADHD 和 ASD 特征连续体的高极端和低极端提供分辨率。使用多项式回归，ADHD 和 ASD 特征与父母评定的内化和外化行为问题以及认知功能测试相关。
结果
ADHD 和 ASD 特征连续体的低极端与较少的行为问题和更好的认知功能相关，而不是症状极端。
结论
研究低连续体末端的相关性可能会加深我们对适应性行为和认知结果背后机制的理解。
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