Pan Mei-Rong, Zhang Shi-Yu, Chen Cai-Li, Qiu Sun-Wei, Liu Lu, Li Hai-Mei, Zhao Meng-Jie, Dong Min, Si Fei-Fei, Wang Yu-Feng, Qian Qiu-Jin
Peking University Sixth Hospital, Peking University Institute of Mental Health, Beijing, China.
NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.
Front Psychiatry. 2023 Jul 19;14:1200522. doi: 10.3389/fpsyt.2023.1200522. eCollection 2023.
BACKGROUND/OBJECTIVES: Adults with attention-deficit/hyperactivity disorder (ADHD) have more maladaptive cognitions, emotional problems and a poorer quality of life (QoL). A verification of the psychological model in clinical samples is needed for a better understanding of the mechanisms of ADHD diagnosis on QoL via maladaptive cognitions, emotional symptoms, and their interactions.
299 ADHD participants and 122 healthy controls were recruited. ADHD core symptoms, maladaptive cognitions, emotional symptoms and psychological QoL were rated. Pearson's correlation and structural equation modeling were analyzed to explore the relationship and influence of ADHD diagnosis on QoL.
More maladaptive cognitions, emotional symptoms, and poorer QoL were found in the ADHD group, and the dysfunctional attitudes were on par between ADHD with or without medication ( = 0.368). Moderate to strong correlations were found between emotional symptoms, maladaptive cognitions and QoL, and ADHD core symptoms presented correlations among the above scores ( = 0.157 ~ 0.416, < 0.01) in ADHD participants. The influence of ADHD diagnosis on QoL was mediated through maladaptive cognitions, emotional symptoms, and their bidirectional interactions ( < 0.05), especially those with stable medication.
Our study is the first to verify the psychological model in adults with ADHD in China. The findings determined the direct influence of ADHD diagnosis on QoL and the indirect influence through maladaptive cognitions, emotional symptoms, and their interactions, emphasizing the importance of interventions for emotional symptoms and maladaptive cognitions for ADHD patients both with or without medication for a better QoL outcome.
背景/目的:患有注意力缺陷多动障碍(ADHD)的成年人具有更多适应不良的认知、情绪问题和较差的生活质量(QoL)。为了更好地理解ADHD诊断通过适应不良认知、情绪症状及其相互作用对生活质量的影响机制,需要在临床样本中验证心理模型。
招募了299名ADHD参与者和122名健康对照者。对ADHD核心症状、适应不良认知、情绪症状和心理生活质量进行评分。分析Pearson相关性和结构方程模型,以探讨ADHD诊断与生活质量之间的关系和影响。
ADHD组中发现更多适应不良认知、情绪症状和较差的生活质量,且功能失调态度在接受或未接受药物治疗的ADHD患者中相当(=0.368)。在ADHD参与者中,情绪症状、适应不良认知和生活质量之间存在中度至强相关性,ADHD核心症状在上述评分之间呈现相关性(=0.157~0.416,<0.01)。ADHD诊断对生活质量的影响是通过适应不良认知、情绪症状及其双向相互作用介导的(<0.05),尤其是那些接受稳定药物治疗的患者。
我们的研究首次在中国ADHD成年人中验证了心理模型。研究结果确定了ADHD诊断对生活质量的直接影响以及通过适应不良认知、情绪症状及其相互作用产生的间接影响,强调了对ADHD患者的情绪症状和适应不良认知进行干预的重要性,无论是否用药,以获得更好的生活质量结果。