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南非开普敦创伤性脊髓损伤的发病率及病因:一项基于人群的前瞻性研究。

Incidence and aetiology of traumatic spinal cord injury in Cape Town, South Africa: a prospective, population-based study.

作者信息

Joseph C, Delcarme A, Vlok I, Wahman K, Phillips J, Nilsson Wikmar L

机构信息

Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.

Department of Physiotherapy, University of the Western Cape, Cape Town, South Africa.

出版信息

Spinal Cord. 2015 Sep;53(9):692-6. doi: 10.1038/sc.2015.51. Epub 2015 Mar 31.

Abstract

STUDY DESIGN

Prospective, regional population-based study.

OBJECTIVES

To provide the incidence, aetiology and injury characteristics of traumatic spinal cord injury (TSCI) in the City of Cape Town, South Africa.

SETTING

All government-funded hospitals within the City of Cape Town, South Africa.

METHODS

All survivors of acute TSCI, given that they met the inclusion criteria, were prospectively included for a 1-year period. The International Spinal Cord injury Core Data Set was used and systematically completed by specialist doctors. Further, international standards for neurological classification were adhered to.

RESULTS

In total, 147 cases of acute TSCI were identified and 145 were included in the study. The male to female ratio was 5.9:1 and the mean age was 33.5 years, ranging from 18 to 93. The crude incidence rate was 75.6 per million (95% CI: 64.3-88.8) with assault as the main cause of injury, accounting for 59.3% of the cases, followed by motor vehicle accidents (26.3%) and falls (11.7%). Most injuries occurred in the cervical spine (53.1%), and American Spinal Injury Association Impairment Scale A severity was most common (39.3%) in the cohort.

CONCLUSION

The incidence rate of TSCI in a region of South Africa was high when compared to previously postulated figures for the country. There is a need for primary preventative strategies to target younger men that are exposed to violent activities. A national study is required to learn whether these findings are only locally applicable or generalisable.

摘要

研究设计

前瞻性、基于区域人口的研究。

目的

提供南非开普敦市创伤性脊髓损伤(TSCI)的发病率、病因及损伤特征。

研究地点

南非开普敦市内所有政府资助的医院。

方法

所有符合纳入标准的急性TSCI幸存者被前瞻性纳入研究,为期1年。使用国际脊髓损伤核心数据集,并由专科医生系统地完成填写。此外,遵循神经学分类的国际标准。

结果

共识别出147例急性TSCI病例,其中145例纳入研究。男女比例为5.9:1,平均年龄为33.5岁,范围在18至93岁之间。粗发病率为每百万75.6例(95%可信区间:64.3 - 88.8),袭击是主要损伤原因,占病例的59.3%,其次是机动车事故(26.3%)和跌倒(11.7%)。大多数损伤发生在颈椎(53.1%),美国脊髓损伤协会损伤分级A严重程度在该队列中最为常见(39.3%)。

结论

与该国先前推测的数据相比,南非一个地区的TSCI发病率较高。需要针对接触暴力活动的年轻男性制定一级预防策略。需要进行一项全国性研究,以了解这些发现是仅适用于当地还是具有普遍性。

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