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加拿大不列颠哥伦比亚省外伤性脊髓损伤的流行病学。

The epidemiology of traumatic spinal cord injury in British Columbia, Canada.

机构信息

Division of Spine, Department of Orthopaedics, University of British Columbia and the Combined Neurosurgical and Orthopaedic Spine Program, Vancouver Hospital and Health Sciences Centre, Vancouver, BC, Canada.

出版信息

Spine (Phila Pa 1976). 2012 Feb 15;37(4):321-9. doi: 10.1097/BRS.0b013e31822e5ff8.

Abstract

STUDY DESIGN

Retrospective observational study utilizing prospectively collected population-based data.

OBJECTIVE

To describe the epidemiology and demographics of all patients with traumatic spinal cord injury (TSCI) treated at a single institution, which represents the sole referral center and specialized SCI unit for a population of 4 million people.

SUMMARY OF BACKGROUND DATA

Although many studies report on the epidemiology of TSCI, studies in which patients are prospectively characterized in the acute setting with precise recording of their baseline neurological impairment are uncommon.

METHODS

Data on all patients admitted to a level 1 trauma center with TSCI between 1995 and 2004 were prospectively collected using a customized, fully relational, locally designed, spine database.

RESULTS

The incidence of TSCI averaged 35.7 per million and did not change substantially during 10 years of data collection. However, the median age of TSCI patients increased from 34.5 to 45.5 years during this period. The men-to-women ratio was 4.4:1. In those older than 55 years, cervical-level injuries with incomplete American Spinal Injury Association (ASIA) Impairment Scale (AIS) scores C and D were most common, with men demonstrating predominantly lower cervical injuries and women more likely to exhibit upper cervical injuries. Increasing rates of surgical treatment during 10 years of this study (61.8%-86.4%) were not associated with improvements in mortality rate or length of hospital stay. Patients older than 75 years who presented with an acute TSCI had a mortality rate of 20% while in hospital.

CONCLUSION

The incidence of TSCI in our population has remained remarkably stable, and age-related changes mirror those in the population across 10 years. An increased tendency to surgical treatment during the 10 years of this study has not resulted in concomitant changes in patients' in-hospital mortality or length of stay.

摘要

研究设计

回顾性观察研究,利用前瞻性收集的基于人群的数据。

目的

描述在一家机构治疗的所有创伤性脊髓损伤(TSCI)患者的流行病学和人口统计学特征,该机构是 400 万人口的唯一转诊中心和专门的 SCI 单位。

背景资料总结

尽管许多研究报告了 TSCI 的流行病学,但在急性情况下对患者进行前瞻性特征描述并精确记录其基线神经损伤的研究并不常见。

方法

使用定制的、全关系的、本地设计的脊柱数据库,前瞻性收集 1995 年至 2004 年期间在一级创伤中心因 TSCI 入院的所有患者的数据。

结果

TSCI 的发病率平均为每百万 35.7 例,在 10 年的数据收集期间没有显著变化。然而,TSCI 患者的中位年龄从 34.5 岁增加到 45.5 岁。男女比例为 4.4:1。在 55 岁以上的人群中,不完全的美国脊髓损伤协会(ASIA)损伤量表(AIS)评分 C 和 D 的颈椎损伤最常见,男性主要表现为较低颈椎损伤,女性更可能表现为较高颈椎损伤。在这项研究的 10 年中,手术治疗的比例不断增加(61.8%-86.4%),但与死亡率或住院时间的改善无关。在急性 TSCI 就诊的 75 岁以上患者的住院死亡率为 20%。

结论

我们人群中的 TSCI 发病率一直保持相当稳定,年龄相关的变化反映了 10 年来人群的变化。在这项研究的 10 年中,手术治疗的趋势增加并没有导致患者住院死亡率或住院时间的相应变化。

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