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菲茨帕特里克讲座:乔治三世国王与卟啉症神话——利用计算机诊断对其精神疾病的病因、后果及重新评估

FitzPatrick Lecture: King George III and the porphyria myth - causes, consequences and re-evaluation of his mental illness with computer diagnostics.

作者信息

Peters Timothy

机构信息

Institute of Archaeology and Antiquity, University of Birmingham, UK

出版信息

Clin Med (Lond). 2015 Apr;15(2):168-72. doi: 10.7861/clinmedicine.15-2-168.

Abstract

Recent studies have shown that the claim that King George III suffered from acute porphyria is seriously at fault. This article explores some of the causes of this misdiagnosis and the consequences of the misleading claims, also reporting on the nature of the king's recurrent mental illness according to computer diagnostics. In addition, techniques of cognitive archaeology are used to investigate the nature of the king's final decade of mental illness, which resulted in the appointment of the Prince of Wales as Prince Regent. The results of this analysis confirm that the king suffered from bipolar disorder type I, with a final decade of dementia, due, in part, to the neurotoxicity of his recurrent episodes of acute mania.

摘要

最近的研究表明,声称乔治三世国王患有急性卟啉病的说法存在严重错误。本文探讨了这种误诊的一些原因以及误导性说法的后果,还根据计算机诊断报告了国王复发性精神疾病的性质。此外,认知考古学技术被用于调查国王最后十年精神疾病的性质,这导致威尔士王子被任命为摄政王。分析结果证实,国王患有I型双相情感障碍,在生命的最后十年患有痴呆症,部分原因是他反复发作的急性躁狂症的神经毒性。

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本文引用的文献

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Computer-based diagnosis of illness in historical persons.基于计算机的历史人物疾病诊断。
J R Coll Physicians Edinb. 2013;43(2):161-8. doi: 10.4997/JRCPE.2013.215.

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