PET/CT扫描对肺癌早期检测的分析
Analysis on early detection of lung cancer by PET/CT scan.
作者信息
Wang Huo-Qiang, Zhao Long, Zhao Juan, Wang Qiang
机构信息
Department of Nuclear Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China E-mail :
出版信息
Asian Pac J Cancer Prev. 2015;16(6):2215-7. doi: 10.7314/apjcp.2015.16.6.2215.
BACKGROUND
This systemic analysis was conducted to to evaluate the application value of positron emission tomography/computed tomography (PET/CT) in early diagnosis of lung cancer.
METHODS
Clinical studies evaluating the application value of PET/CT for patients underwent PET/CT imaging. The histological diagnosis served as the standard of truth.
RESULTS
Four clinical studies which including 1330 patients with pulmonary space- occupying lesions were considered eligible for inclusion. Systemic analysis suggested that, in all 1330 patients, pooled sensitivity was 98.7% (1313.2/1330) and specificity was 58.2%(276.85/476).
CONCLUSION
This systemic analysis suggests that integrated PET/CT imaging provides high sensitivity, and reasonably high specificity, and could be applied for early diagnosis of lung cancer.
背景
进行这项系统分析以评估正电子发射断层扫描/计算机断层扫描（PET/CT）在肺癌早期诊断中的应用价值。
方法
对接受PET/CT成像的患者进行评估PET/CT应用价值的临床研究。组织学诊断作为金标准。
结果
四项临床研究共纳入1330例肺部占位性病变患者。系统分析表明，在所有1330例患者中，合并敏感度为98.7%（1313.2/1330），特异度为58.2%（276.85/476）。
结论
该系统分析表明，PET/CT融合成像具有较高的敏感度和合理的特异度，可用于肺癌的早期诊断。
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