Atoba M A, Olubuyide I O
Cent Afr J Med. 1989 Jul;35(7):427-30.
The effect of 4 non-steroidal anti-inflammatory agents, viz Aspirin, Piroxicam, Ibuprofen and Indomethacin on the gastric mucosa of the African was studied on 34 volunteers who had no previous symptoms of acid peptic diseases. Aspirin caused the worst lesions while piroxicam caused the least lesions. The indiscriminate prescription of these drugs, particularly drugs containing acetosalicylic acid should be avoided.
研究了4种非甾体抗炎药，即阿司匹林、吡罗昔康、布洛芬和吲哚美辛对34名既往无酸相关性疾病症状的非洲志愿者胃黏膜的影响。阿司匹林造成的损伤最严重，而吡罗昔康造成的损伤最小。应避免滥用这些药物，尤其是含乙酰水杨酸的药物。
