Yu J Y
Zhonghua Bing Li Xue Za Zhi. 1989 Jun;18(2):121-4.
210 various colo-rectal polyps including 46 inflammatory polyps, 21 juvenile polyps, 9 hyperplastic polyps, 65 tubular adenomas, 51 familial polyps, 11 villous adenomas, 7 adenomatous polyps with focal cancer, and 14 carcinoma of the large bowel were investigated by HE,HID-AB,PAT-KOH-PAS staining in order to study the mucin changes of these lesions. N-acetylated and C7,C9 O-acetylated sialomucin were mainly obtained in those adenomas with moderate and severe dysplasia (55-64.3%) and the proportion was even higher in cases of villous adenomas, familial polyps, adenomas with focal cancer and advanced carcinoma. These mucins might be assumed as a criteria in representing malignant transformation.
对210例各种结直肠息肉进行了研究，其中包括46例炎性息肉、21例幼年性息肉、9例增生性息肉、65例管状腺瘤、51例家族性息肉、11例绒毛状腺瘤、7例局灶性癌性腺瘤性息肉以及14例大肠癌，采用苏木精-伊红（HE）、高铁二胺-阿尔辛蓝（HID-AB）、过碘酸-氢氧化钾-过碘酸雪夫（PAT-KOH-PAS）染色，以研究这些病变的黏蛋白变化。N-乙酰化和C7、C9 O-乙酰化唾液黏蛋白主要在中度和重度发育异常的腺瘤中出现（55%-64.3%），在绒毛状腺瘤、家族性息肉、局灶性癌性腺瘤和进展期癌病例中的比例更高。这些黏蛋白可能被视为代表恶性转化的一个标准。
