Budu Vlad Andrei, Bulescu Ioan Alexandru, Popp Cristiana Gabriela, Mocanu Bogdan Constantin, Mogoantă Carmen Aurelia
Department of Anatomy, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania;
Rom J Morphol Embryol. 2015;56(1):273-6.
Tumors of the parapharyngeal space are rare accounting approximately for 0.5% of all head and neck tumors. In the retrostyloid space, schwannomas are a more common finding, in contrast to other tumors. Usually, they present with a variety of slight symptoms until they grow in size and compress surrounding organs. Surgical treatment of parapharyngeal space tumors is difficult; due to the anatomical complex area, they develop in, and include several approaches, according to its size and relations. In this paper, we present a case of a 63-year-old female with a vagus nerve schwannoma in the parapharyngeal space. Beside the surgical difficulties, the resected tumor had a peculiar histopathological aspect (large areas of degeneration and atypia and little typical palisading) that compelled a thorough histological and immunohistochemical evaluation for positive and differential diagnosis.
咽旁间隙肿瘤较为罕见，约占所有头颈肿瘤的0.5%。与其他肿瘤相比，在茎突后间隙，神经鞘瘤更为常见。通常，它们在长大并压迫周围器官之前会出现各种轻微症状。咽旁间隙肿瘤的手术治疗具有挑战性；由于其所在的解剖区域复杂，根据肿瘤大小及关系，有多种手术入路。本文报告一例63岁女性，患有咽旁间隙迷走神经鞘瘤。除了手术困难外，切除的肿瘤具有特殊的组织病理学表现（大片变性和异型性，典型的栅栏状结构较少），这使得有必要进行全面的组织学和免疫组化评估以进行阳性和鉴别诊断。
