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Ofatumumab and its role as immunotherapy in chronic lymphocytic leukemia.

作者信息

Sandhu Suneet, Mulligan Stephen P

机构信息

Department of Haematology, Royal North Shore Hospital, St Leonards, NSW Kolling Institute, University of Sydney, St Leonards, NSW, Australia.

Department of Haematology, Royal North Shore Hospital, St Leonards, NSW Kolling Institute, University of Sydney, St Leonards, NSW, Australia

出版信息

Haematologica. 2015 Apr;100(4):411-4. doi: 10.3324/haematol.2015.124107.

DOI:10.3324/haematol.2015.124107
PMID:25828085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4380711/
Abstract
摘要

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Ofatumumab added to dexamethasone in patients with relapsed or refractory chronic lymphocytic leukemia: Results from a phase II study.奥法妥木单抗联合地塞米松治疗复发或难治性慢性淋巴细胞白血病患者:一项 II 期研究结果。
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Obinutuzumab as frontline treatment of chronic lymphocytic leukemia: updated results of the CLL11 study.奥妥珠单抗作为慢性淋巴细胞白血病的一线治疗:CLL11研究的更新结果。
Leukemia. 2015 Jul;29(7):1602-4. doi: 10.1038/leu.2015.14. Epub 2015 Jan 30.
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Ofatumumab in poor-prognosis chronic lymphocytic leukemia: a phase IV, non-interventional, observational study from the European Research Initiative on Chronic Lymphocytic Leukemia.奥法木单抗治疗预后不良的慢性淋巴细胞白血病:一项来自欧洲慢性淋巴细胞白血病研究倡议的IV期非干预性观察性研究。
Haematologica. 2015 Apr;100(4):511-6. doi: 10.3324/haematol.2014.118158. Epub 2015 Jan 16.
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Sequential ofatumumab and lenalidomide for the treatment of relapsed and refractory chronic lymphocytic leukemia and small lymphocytic lymphoma.序贯使用奥法妥木单抗和来那度胺治疗复发难治性慢性淋巴细胞白血病和小淋巴细胞淋巴瘤。
Leuk Lymphoma. 2015 Mar;56(3):645-9. doi: 10.3109/10428194.2014.935369.
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Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia.伊布替尼与奥法妥木单抗治疗既往治疗的慢性淋巴细胞白血病。
N Engl J Med. 2014 Jul 17;371(3):213-23. doi: 10.1056/NEJMoa1400376. Epub 2014 May 31.
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Leukemia. 2014 Mar;28(3):642-8. doi: 10.1038/leu.2013.334. Epub 2013 Nov 13.
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Blood. 2011 Jun 16;117(24):6450-8. doi: 10.1182/blood-2010-12-323980. Epub 2011 Apr 15.
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Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia.奥法妥木单抗作为单一药物 CD20 免疫疗法在氟达拉滨难治性慢性淋巴细胞白血病中的应用。
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